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• W2091060891 abstract "Forty years ago, a simple model of allosteric mechanisms (indirect interactions between distinct sites), used initially to explain feedback-inhibited enzymes, was presented by Monod, Wyman, and Changeux. We review the MWC theory and its applications for the understanding of signal transduction in biology, and also identify remaining issues that deserve theoretical and experimental substantiation." @default.
• W2091060891 created "2016-06-24" @default.
• W2091060891 creator A5015140013 @default.
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• W2091060891 date "2005-06-03" @default.
• W2091060891 modified "2023-10-16" @default.
• W2091060891 title "Allosteric Mechanisms of Signal Transduction" @default.
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• W2091060891 doi "https://doi.org/10.1126/science.1108595" @default.
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