Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091074667> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2091074667 endingPage "41" @default.
- W2091074667 startingPage "37" @default.
- W2091074667 abstract "Rings of canine basilar arteries with and without endothelium were suspended for isometric tension recording in modified Krebs-Ringer bicarbonate solution. Increased extracellular concentrations of potassium (3-20 mM) caused rhythmic activity in rings with endothelium. This activity was reduced by the removal of the endothelium and by exposure to indomethacin, meclofenamate, diltiazem, or ouabain; it was not affected by tetrodotoxin, bretylium tosylate, phentolamine, propranolol, atropine, methiothepin, and cimetidine. Prostaglandin F2 alpha and E2 caused concentration-dependent increases in the frequency and the amplitude of this rhythmic activity and reversed the inhibitory effect of indomethacin and meclofenamate. Prostacyclin abolished the activity. These results suggest that increasing the concentration of extracellular potassium causes rhythmic activity in canine basilar arteries because of the production and/or release by the endothelium of products of cyclooxygenase such as prostaglandin F2 alpha and E2. These may initiate the contraction while prostacyclin triggers the relaxation phase of the rhythmic activity, possibly by activating Na+, K+-ATPase of the vascular smooth muscle." @default.
- W2091074667 created "2016-06-24" @default.
- W2091074667 creator A5004710314 @default.
- W2091074667 creator A5040748119 @default.
- W2091074667 creator A5082346434 @default.
- W2091074667 date "1988-07-01" @default.
- W2091074667 modified "2023-09-26" @default.
- W2091074667 title "Potassium-Induced Endothelium-Dependent Rhythmic Activity in the Canine Basilar Artery" @default.
- W2091074667 doi "https://doi.org/10.1097/00005344-198807000-00005" @default.
- W2091074667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2459532" @default.
- W2091074667 hasPublicationYear "1988" @default.
- W2091074667 type Work @default.
- W2091074667 sameAs 2091074667 @default.
- W2091074667 citedByCount "40" @default.
- W2091074667 countsByYear W20910746672020 @default.
- W2091074667 crossrefType "journal-article" @default.
- W2091074667 hasAuthorship W2091074667A5004710314 @default.
- W2091074667 hasAuthorship W2091074667A5040748119 @default.
- W2091074667 hasAuthorship W2091074667A5082346434 @default.
- W2091074667 hasBestOaLocation W20910746671 @default.
- W2091074667 hasConcept C126322002 @default.
- W2091074667 hasConcept C134018914 @default.
- W2091074667 hasConcept C163415756 @default.
- W2091074667 hasConcept C178790620 @default.
- W2091074667 hasConcept C185592680 @default.
- W2091074667 hasConcept C2776741139 @default.
- W2091074667 hasConcept C2776741303 @default.
- W2091074667 hasConcept C2776992346 @default.
- W2091074667 hasConcept C2778151854 @default.
- W2091074667 hasConcept C2779133857 @default.
- W2091074667 hasConcept C2780253649 @default.
- W2091074667 hasConcept C2781012200 @default.
- W2091074667 hasConcept C2781128415 @default.
- W2091074667 hasConcept C519063684 @default.
- W2091074667 hasConcept C537181965 @default.
- W2091074667 hasConcept C71924100 @default.
- W2091074667 hasConceptScore W2091074667C126322002 @default.
- W2091074667 hasConceptScore W2091074667C134018914 @default.
- W2091074667 hasConceptScore W2091074667C163415756 @default.
- W2091074667 hasConceptScore W2091074667C178790620 @default.
- W2091074667 hasConceptScore W2091074667C185592680 @default.
- W2091074667 hasConceptScore W2091074667C2776741139 @default.
- W2091074667 hasConceptScore W2091074667C2776741303 @default.
- W2091074667 hasConceptScore W2091074667C2776992346 @default.
- W2091074667 hasConceptScore W2091074667C2778151854 @default.
- W2091074667 hasConceptScore W2091074667C2779133857 @default.
- W2091074667 hasConceptScore W2091074667C2780253649 @default.
- W2091074667 hasConceptScore W2091074667C2781012200 @default.
- W2091074667 hasConceptScore W2091074667C2781128415 @default.
- W2091074667 hasConceptScore W2091074667C519063684 @default.
- W2091074667 hasConceptScore W2091074667C537181965 @default.
- W2091074667 hasConceptScore W2091074667C71924100 @default.
- W2091074667 hasIssue "1" @default.
- W2091074667 hasLocation W20910746671 @default.
- W2091074667 hasLocation W20910746672 @default.
- W2091074667 hasLocation W20910746673 @default.
- W2091074667 hasOpenAccess W2091074667 @default.
- W2091074667 hasPrimaryLocation W20910746671 @default.
- W2091074667 hasRelatedWork W1970679878 @default.
- W2091074667 hasRelatedWork W2000782571 @default.
- W2091074667 hasRelatedWork W2001904678 @default.
- W2091074667 hasRelatedWork W2057537203 @default.
- W2091074667 hasRelatedWork W2091022983 @default.
- W2091074667 hasRelatedWork W2091074667 @default.
- W2091074667 hasRelatedWork W2093919627 @default.
- W2091074667 hasRelatedWork W2135033561 @default.
- W2091074667 hasRelatedWork W2255791654 @default.
- W2091074667 hasRelatedWork W4243979506 @default.
- W2091074667 hasVolume "12" @default.
- W2091074667 isParatext "false" @default.
- W2091074667 isRetracted "false" @default.
- W2091074667 magId "2091074667" @default.
- W2091074667 workType "article" @default.