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• W2091094573 abstract "An electron microscopic study of Coxsackievirus B3-infected newborn mice revealed pathological changes in both the endocrine and exocrine portions of the pancreas. Damage ranged from a focal degeneration in which small areas of individual cells were affected to a widespread necrosis and inflammation in which entire acini and islets were so changed that identification of individual cell types was difficult. Compound membrane-vesicle complexes typical of picornavirus infection and virus particles in various arrays were observed in the acinar cells and macrophages. Fibrosis of the islets and a thickening of the basal laminae of associated capillaries were noted also. Comparisons were made to the pancreatitis caused by this and other group B Coxsackieviruses in both human and experimental animals." @default.
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• W2091094573 date "1972-10-01" @default.
• W2091094573 modified "2023-09-28" @default.
• W2091094573 title "Viral pancreatitis: Ultrastructural pathological effects of coxsackievirus B3 infection in newborn mouse pancreas" @default.
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• W2091094573 doi "https://doi.org/10.1016/0014-4800(72)90070-6" @default.
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