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- W2091110069 abstract "We present a case of del(14)(q21) as a sole abnormality in a 4-year-old boy diagnosed with precursor B-cell acute lymphoblastic leukemia (pre-B ALL). To our knowledge, this is the first case of isolated del(14)(q21) in pre-B ALL. Two pretreatment bone marrow samples obtained 5 days apart were analyzed by cytogenetics. The G-banded karyotypes of the two samples were similar, differing only in the ratio of normal/abnormal metaphases detected. Both samples showed a del(14)(q21) as the only abnormality. Fluorescence in situ hybridization performed using the probes TEL/AML1 and immunoglobulin heavy chain (IGH) showed no fusion involving the TEL and AML1 genes and only a single IGH signal in 20% of the interphase cells analyzed." @default.
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- W2091110069 date "2005-08-01" @default.
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- W2091110069 title "Isolated del(14)(q21) in a case of precursor B-cell acute lymphoblastic leukemia" @default.
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- W2091110069 doi "https://doi.org/10.1016/j.cancergencyto.2004.12.022" @default.
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