FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091131449> ?p ?o ?g. }

• W2091131449 endingPage "e69664" @default.
• W2091131449 startingPage "e69664" @default.
• W2091131449 abstract "Adhesion to digestive mucosa is considered a crucial first step in the pathogenicity of invasive Candida infections. Candida glabrata disseminated infections predominantly start from the gut. A mouse model of disseminated infection starting from the gut was set up. Hematogenous dissemination was obtained after a low-protein diet followed by a regimen of cyclophosphamide-methotrexate and an oral inoculation of the yeasts via the drinking water. The liver was the first organ infected (day 7 post-infection), and lethality was 100% at day 21 post-infection. This new mouse model was used to compare the mortality rate and fungal burden in deep organs induced by 5 strains exhibiting different levels of adhesion to enterocyte Caco-2 cells, as determined in a test on 36 C. glabrata strains. In this model, no statistical difference of lethality was demonstrated between the strains, and fungal burden varied in kidneys and lungs but without correlation with the level of adhesion to enterocytes. Further studies using the model developed here allow analysis of the crossing of the digestive mucosa by yeasts, and help relate this to yet-poorly understood adhesion phenotypes." @default.
• W2091131449 created "2016-06-24" @default.
• W2091131449 creator A5003698488 @default.
• W2091131449 creator A5028353199 @default.
• W2091131449 creator A5040606259 @default.
• W2091131449 creator A5046190908 @default.
• W2091131449 creator A5057234416 @default.
• W2091131449 creator A5065315682 @default.
• W2091131449 creator A5075766838 @default.
• W2091131449 creator A5077020153 @default.
• W2091131449 date "2013-07-23" @default.
• W2091131449 modified "2023-10-16" @default.
• W2091131449 title "A Mouse Model for Candida glabrata Hematogenous Disseminated Infection Starting from the Gut: Evaluation of Strains with Different Adhesion Properties" @default.
• W2091131449 cites W1537995961 @default.
• W2091131449 cites W1594622192 @default.
• W2091131449 cites W1965402075 @default.
• W2091131449 cites W1986702564 @default.
• W2091131449 cites W1992994480 @default.
• W2091131449 cites W2002836781 @default.
• W2091131449 cites W2008240603 @default.
• W2091131449 cites W2008888079 @default.
• W2091131449 cites W2009509881 @default.
• W2091131449 cites W2012600634 @default.
• W2091131449 cites W2016262551 @default.
• W2091131449 cites W2028527480 @default.
• W2091131449 cites W2032893561 @default.
• W2091131449 cites W2035923800 @default.
• W2091131449 cites W2061823928 @default.
• W2091131449 cites W2062983075 @default.
• W2091131449 cites W2075016274 @default.
• W2091131449 cites W2078752695 @default.
• W2091131449 cites W2098964280 @default.
• W2091131449 cites W2099624816 @default.
• W2091131449 cites W2102496935 @default.
• W2091131449 cites W2129005725 @default.
• W2091131449 cites W2139728976 @default.
• W2091131449 cites W2141007876 @default.
• W2091131449 cites W2142203500 @default.
• W2091131449 cites W2143839871 @default.
• W2091131449 cites W2145577370 @default.
• W2091131449 cites W2149460185 @default.
• W2091131449 cites W2149855320 @default.
• W2091131449 cites W2150187215 @default.
• W2091131449 cites W2154975007 @default.
• W2091131449 cites W2158717508 @default.
• W2091131449 cites W2158917850 @default.
• W2091131449 cites W2169395719 @default.
• W2091131449 cites W63367705 @default.
• W2091131449 doi "https://doi.org/10.1371/journal.pone.0069664" @default.
• W2091131449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3720583" @default.
• W2091131449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23936069" @default.
• W2091131449 hasPublicationYear "2013" @default.
• W2091131449 type Work @default.
• W2091131449 sameAs 2091131449 @default.
• W2091131449 citedByCount "16" @default.
• W2091131449 countsByYear W20911314492014 @default.
• W2091131449 countsByYear W20911314492015 @default.
• W2091131449 countsByYear W20911314492017 @default.
• W2091131449 countsByYear W20911314492019 @default.
• W2091131449 countsByYear W20911314492020 @default.
• W2091131449 countsByYear W20911314492021 @default.
• W2091131449 countsByYear W20911314492022 @default.
• W2091131449 crossrefType "journal-article" @default.
• W2091131449 hasAuthorship W2091131449A5003698488 @default.
• W2091131449 hasAuthorship W2091131449A5028353199 @default.
• W2091131449 hasAuthorship W2091131449A5040606259 @default.
• W2091131449 hasAuthorship W2091131449A5046190908 @default.
• W2091131449 hasAuthorship W2091131449A5057234416 @default.
• W2091131449 hasAuthorship W2091131449A5065315682 @default.
• W2091131449 hasAuthorship W2091131449A5075766838 @default.
• W2091131449 hasAuthorship W2091131449A5077020153 @default.
• W2091131449 hasBestOaLocation W20911314491 @default.
• W2091131449 hasConcept C126322002 @default.
• W2091131449 hasConcept C178790620 @default.
• W2091131449 hasConcept C185592680 @default.
• W2091131449 hasConcept C203014093 @default.
• W2091131449 hasConcept C2777882243 @default.
• W2091131449 hasConcept C2779604457 @default.
• W2091131449 hasConcept C2780670043 @default.
• W2091131449 hasConcept C2780917455 @default.
• W2091131449 hasConcept C3019368612 @default.
• W2091131449 hasConcept C55493867 @default.
• W2091131449 hasConcept C71924100 @default.
• W2091131449 hasConcept C84416704 @default.
• W2091131449 hasConcept C86803240 @default.
• W2091131449 hasConcept C89423630 @default.
• W2091131449 hasConceptScore W2091131449C126322002 @default.
• W2091131449 hasConceptScore W2091131449C178790620 @default.
• W2091131449 hasConceptScore W2091131449C185592680 @default.
• W2091131449 hasConceptScore W2091131449C203014093 @default.
• W2091131449 hasConceptScore W2091131449C2777882243 @default.
• W2091131449 hasConceptScore W2091131449C2779604457 @default.
• W2091131449 hasConceptScore W2091131449C2780670043 @default.
• W2091131449 hasConceptScore W2091131449C2780917455 @default.
• W2091131449 hasConceptScore W2091131449C3019368612 @default.
• W2091131449 hasConceptScore W2091131449C55493867 @default.
• W2091131449 hasConceptScore W2091131449C71924100 @default.
• W2091131449 hasConceptScore W2091131449C84416704 @default.

• next