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- W2091170688 abstract "Four acyclic guanosine analogs, the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine, 9-(4-hydroxybutyl)guanine, and acyclovir were compared in enzyme kinetic experiments, using purified herpes simplex virus type 2 thymidine kinase. All four analogs showed competitive patterns of inhibition in the phosphorylation of thymidine by the viral thymidine kinase, but different affinities and relative rates of phosphorylation were observed." @default.
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- W2091170688 date "1984-04-01" @default.
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- W2091170688 title "Phosphorylation of four acyclic guanosine analogs by herpes simplex virus type 2 thymidine kinase" @default.
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- W2091170688 doi "https://doi.org/10.1128/aac.25.4.524" @default.
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