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- W2091214957 abstract "A unique patient with sideroblastic anemia and thrombocytosis with a recurrent and ultimately fatal thromboembolic phenomenon is described. Cytogenetic analysis of bone marrow metaphases revealed a pseudodiploid chromosome complement, 46,XY,ins(3;3)(q26;q21q26). The association of thrombocytosis and ins(3;3) in patients with preleukemia or myelogenous leukemia has been reported previously. The association of ins(3;3) and thrombocytosis in our patient with sideroblastic anemia suggests that the disorder may involve a hematopoietic progenitor cell capable of giving rise to all three cell lineages. Our findings also support the suggestion that a gene on the long arm of chromosome #3 may encode a protein that, at least in part, regulates megakaryopoiesis." @default.
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- W2091214957 date "1986-06-01" @default.
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- W2091214957 title "Sideroblastic anemia associated with thrombocytosis and a chromosome 3 abnormality" @default.
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- W2091214957 doi "https://doi.org/10.1016/0165-4608(86)90205-0" @default.
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