FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091217768> ?p ?o ?g. }

• W2091217768 endingPage "1163" @default.
• W2091217768 startingPage "1152" @default.
• W2091217768 abstract "The human system L-amino acid transporter1 (hLAT1) is one of the CD98 light chains and its gene has been mapped to chromosome 16q24. Our preliminary findings have indicated that in HeLa S3 cells there are transcripts whose nucleotide sequences are very similar but not identical to that of the amino acid transporter. This study intends to examine whether these novel transcripts have biological significance through elucidating their genetic aspects and expression profiles in human cells.The expression levels of the transcripts were quantified by real-time PCR analysis. Chromosomal mapping of the gene was performed by fluorescence in situ hybridization (FISH).Three types of transcripts were identified and their nucleotide sequences were aligned with the chromosome 16p12 clone with high identity. They encoded 180- or 190-amino acid proteins, showing 92-94% of amino acid identity to the amino-terminal region of the hLAT1 (507 amino acids). However, their 3' non-coding sequences did not show homology to the nucleotide sequence of the amino acid transporter. Their genes were mapped to chromosome 16p11.2-p13.1 as low-copy repeats (LCRs). The transcription of one of these genes in peripheral blood mononuclear cells was significantly up-regulated when the cells were stimulated with concanavalin A.We have characterized the three truncated paralogs of the hLAT1 gene. It is suggested that the expression of one of these paralogs may play an important role in the activation of peripheral blood mononuclear cells." @default.
• W2091217768 created "2016-06-24" @default.
• W2091217768 creator A5001644765 @default.
• W2091217768 creator A5002209181 @default.
• W2091217768 creator A5012096259 @default.
• W2091217768 creator A5012445152 @default.
• W2091217768 creator A5025893853 @default.
• W2091217768 creator A5045120554 @default.
• W2091217768 creator A5051683179 @default.
• W2091217768 creator A5054233331 @default.
• W2091217768 creator A5090958418 @default.
• W2091217768 date "2002-09-01" @default.
• W2091217768 modified "2023-10-14" @default.
• W2091217768 title "Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system l-amino acid transporter 1" @default.
• W2091217768 cites W1488035272 @default.
• W2091217768 cites W1540095279 @default.
• W2091217768 cites W1541425590 @default.
• W2091217768 cites W1552025227 @default.
• W2091217768 cites W1560843753 @default.
• W2091217768 cites W1569593364 @default.
• W2091217768 cites W1575813177 @default.
• W2091217768 cites W1582359873 @default.
• W2091217768 cites W1601032788 @default.
• W2091217768 cites W1613701641 @default.
• W2091217768 cites W1651672993 @default.
• W2091217768 cites W1785514879 @default.
• W2091217768 cites W1847283821 @default.
• W2091217768 cites W1975363517 @default.
• W2091217768 cites W1976678735 @default.
• W2091217768 cites W1977300744 @default.
• W2091217768 cites W1982958681 @default.
• W2091217768 cites W1986476951 @default.
• W2091217768 cites W1986709822 @default.
• W2091217768 cites W1989350647 @default.
• W2091217768 cites W1996045753 @default.
• W2091217768 cites W1998661404 @default.
• W2091217768 cites W2016391435 @default.
• W2091217768 cites W2044797653 @default.
• W2091217768 cites W2045317687 @default.
• W2091217768 cites W2045348184 @default.
• W2091217768 cites W2057262265 @default.
• W2091217768 cites W2068332030 @default.
• W2091217768 cites W2075764674 @default.
• W2091217768 cites W2080292234 @default.
• W2091217768 cites W2082141452 @default.
• W2091217768 cites W2140500849 @default.
• W2091217768 cites W2147385203 @default.
• W2091217768 cites W2413785026 @default.
• W2091217768 cites W38751632 @default.
• W2091217768 doi "https://doi.org/10.1016/s1357-2725(02)00036-5" @default.
• W2091217768 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12009310" @default.
• W2091217768 hasPublicationYear "2002" @default.
• W2091217768 type Work @default.
• W2091217768 sameAs 2091217768 @default.
• W2091217768 citedByCount "5" @default.
• W2091217768 crossrefType "journal-article" @default.
• W2091217768 hasAuthorship W2091217768A5001644765 @default.
• W2091217768 hasAuthorship W2091217768A5002209181 @default.
• W2091217768 hasAuthorship W2091217768A5012096259 @default.
• W2091217768 hasAuthorship W2091217768A5012445152 @default.
• W2091217768 hasAuthorship W2091217768A5025893853 @default.
• W2091217768 hasAuthorship W2091217768A5045120554 @default.
• W2091217768 hasAuthorship W2091217768A5051683179 @default.
• W2091217768 hasAuthorship W2091217768A5054233331 @default.
• W2091217768 hasAuthorship W2091217768A5090958418 @default.
• W2091217768 hasConcept C104317684 @default.
• W2091217768 hasConcept C149011108 @default.
• W2091217768 hasConcept C150194340 @default.
• W2091217768 hasConcept C153911025 @default.
• W2091217768 hasConcept C165525559 @default.
• W2091217768 hasConcept C167625842 @default.
• W2091217768 hasConcept C2777542201 @default.
• W2091217768 hasConcept C2781313199 @default.
• W2091217768 hasConcept C30481170 @default.
• W2091217768 hasConcept C515207424 @default.
• W2091217768 hasConcept C54355233 @default.
• W2091217768 hasConcept C84148353 @default.
• W2091217768 hasConcept C86803240 @default.
• W2091217768 hasConceptScore W2091217768C104317684 @default.
• W2091217768 hasConceptScore W2091217768C149011108 @default.
• W2091217768 hasConceptScore W2091217768C150194340 @default.
• W2091217768 hasConceptScore W2091217768C153911025 @default.
• W2091217768 hasConceptScore W2091217768C165525559 @default.
• W2091217768 hasConceptScore W2091217768C167625842 @default.
• W2091217768 hasConceptScore W2091217768C2777542201 @default.
• W2091217768 hasConceptScore W2091217768C2781313199 @default.
• W2091217768 hasConceptScore W2091217768C30481170 @default.
• W2091217768 hasConceptScore W2091217768C515207424 @default.
• W2091217768 hasConceptScore W2091217768C54355233 @default.
• W2091217768 hasConceptScore W2091217768C84148353 @default.
• W2091217768 hasConceptScore W2091217768C86803240 @default.
• W2091217768 hasIssue "9" @default.
• W2091217768 hasLocation W20912177681 @default.
• W2091217768 hasLocation W20912177682 @default.
• W2091217768 hasOpenAccess W2091217768 @default.
• W2091217768 hasPrimaryLocation W20912177681 @default.
• W2091217768 hasRelatedWork W1982964306 @default.
• W2091217768 hasRelatedWork W2028934005 @default.

• next