FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091218527> ?p ?o ?g. }

• W2091218527 endingPage "S170" @default.
• W2091218527 startingPage "S170" @default.
• W2091218527 abstract "We have conducted a clinical trial to evaluate the short course whole breast irradiation to be equally effective and safe and have the advantage in the point of convenience in comparison with conventional fractionation radiotherapy. In this study, we compared the acute skin reactions between both arms. Patients eligible for this study were as follows: breast cancer, Stage 0 to II; surgical intervention to the breast, lumpectomy or quadrantectomy; surgical intervention to the axilla, axillary node dissection or sentinel lymph node biopsy; positive lymph nodes, less than 3; concurrent chemotherapy, none. Prior to the treatment, all patients were explained about the merit and demerit of the two treatment schedules and the patients chose the irradiation schedule freely. The short course irradiation consisted of 43.2 Gy/16f (2.7 Gy/f) to the whole breast, with additional tumor bed boost of 8.1 Gy/3f if the surgical margin was positive or less than 5 mm. The conventional course irradiation consisted of 50 Gy/25f (2 Gy/f) to the whole breast, with additional tumor bed boost of 10 Gy/5f if the surgical margin was positive or less than 5 mm or 6 Gy/3f if the surgical margin was negative, which has been our standard of care. All breasts are irradiated with 4 MV photon tangential fields using sliding window technique IMRT. The inhomogeneity of PTV are planned to be less than 10% (between 105% and 95%). The acute adverse effects have been evaluated weekly during treatment and 1 week after the completion of treatment. Between April 1, 2006 and December 31, 2007, 507 cases were registered. Among them, 249 cases (49%) were short course and 258 cases (51%) were conventional course. The cases with positive or closed surgical margins were 107 cases (43%) in short course and 152 cases (59%) in conventional course. Menopausal status was pre in 224 cases (44%) and post in 283 cases (56%). Primary systemic chemotherapy was given in 137 cases (27%) and concurrent endocrine therapy was given in 144 cases (28%). Grade 2 acute skin reactions were observed in 9 cases (4%) in short course and 64 cases (25%) in conventional course (p < 0.001). Factors showed strong correlation with acute skin reactions were menopausal status (in the postmenopausal patients, it was significantly low. p < 0.001) and total doses. In phantom study, IMRT improved homogeneity of surface dose over 10% in maximum point than physical wedge. The short course whole breast irradiation was not only convenient but also superior for less acute skin reaction in using sliding window technique IMRT." @default.
• W2091218527 created "2016-06-24" @default.
• W2091218527 creator A5006801669 @default.
• W2091218527 creator A5024706642 @default.
• W2091218527 creator A5027332666 @default.
• W2091218527 creator A5028206707 @default.
• W2091218527 creator A5030517670 @default.
• W2091218527 creator A5043232476 @default.
• W2091218527 creator A5050615106 @default.
• W2091218527 creator A5065792089 @default.
• W2091218527 creator A5066700160 @default.
• W2091218527 creator A5084017688 @default.
• W2091218527 date "2008-09-01" @default.
• W2091218527 modified "2023-09-26" @default.
• W2091218527 title "Comparison of Acute Skin Reaction between Short Course and Conventional Fractionation Radiotherapy in Breast Conserving Therapy" @default.
• W2091218527 doi "https://doi.org/10.1016/j.ijrobp.2008.06.720" @default.
• W2091218527 hasPublicationYear "2008" @default.
• W2091218527 type Work @default.
• W2091218527 sameAs 2091218527 @default.
• W2091218527 citedByCount "0" @default.
• W2091218527 crossrefType "journal-article" @default.
• W2091218527 hasAuthorship W2091218527A5006801669 @default.
• W2091218527 hasAuthorship W2091218527A5024706642 @default.
• W2091218527 hasAuthorship W2091218527A5027332666 @default.
• W2091218527 hasAuthorship W2091218527A5028206707 @default.
• W2091218527 hasAuthorship W2091218527A5030517670 @default.
• W2091218527 hasAuthorship W2091218527A5043232476 @default.
• W2091218527 hasAuthorship W2091218527A5050615106 @default.
• W2091218527 hasAuthorship W2091218527A5065792089 @default.
• W2091218527 hasAuthorship W2091218527A5066700160 @default.
• W2091218527 hasAuthorship W2091218527A5084017688 @default.
• W2091218527 hasBestOaLocation W20912185271 @default.
• W2091218527 hasConcept C121608353 @default.
• W2091218527 hasConcept C126322002 @default.
• W2091218527 hasConcept C126838900 @default.
• W2091218527 hasConcept C141071460 @default.
• W2091218527 hasConcept C155806632 @default.
• W2091218527 hasConcept C2775934546 @default.
• W2091218527 hasConcept C2776608951 @default.
• W2091218527 hasConcept C2777757722 @default.
• W2091218527 hasConcept C2778115633 @default.
• W2091218527 hasConcept C2779572924 @default.
• W2091218527 hasConcept C2989005 @default.
• W2091218527 hasConcept C509974204 @default.
• W2091218527 hasConcept C530470458 @default.
• W2091218527 hasConcept C71924100 @default.
• W2091218527 hasConceptScore W2091218527C121608353 @default.
• W2091218527 hasConceptScore W2091218527C126322002 @default.
• W2091218527 hasConceptScore W2091218527C126838900 @default.
• W2091218527 hasConceptScore W2091218527C141071460 @default.
• W2091218527 hasConceptScore W2091218527C155806632 @default.
• W2091218527 hasConceptScore W2091218527C2775934546 @default.
• W2091218527 hasConceptScore W2091218527C2776608951 @default.
• W2091218527 hasConceptScore W2091218527C2777757722 @default.
• W2091218527 hasConceptScore W2091218527C2778115633 @default.
• W2091218527 hasConceptScore W2091218527C2779572924 @default.
• W2091218527 hasConceptScore W2091218527C2989005 @default.
• W2091218527 hasConceptScore W2091218527C509974204 @default.
• W2091218527 hasConceptScore W2091218527C530470458 @default.
• W2091218527 hasConceptScore W2091218527C71924100 @default.
• W2091218527 hasIssue "1" @default.
• W2091218527 hasLocation W20912185271 @default.
• W2091218527 hasOpenAccess W2091218527 @default.
• W2091218527 hasPrimaryLocation W20912185271 @default.
• W2091218527 hasRelatedWork W2045742295 @default.
• W2091218527 hasRelatedWork W2059347310 @default.
• W2091218527 hasRelatedWork W2073937368 @default.
• W2091218527 hasRelatedWork W2088894222 @default.
• W2091218527 hasRelatedWork W2409321565 @default.
• W2091218527 hasRelatedWork W2412192075 @default.
• W2091218527 hasRelatedWork W2528976349 @default.
• W2091218527 hasRelatedWork W304623792 @default.
• W2091218527 hasRelatedWork W3151238415 @default.
• W2091218527 hasRelatedWork W97258751 @default.
• W2091218527 hasVolume "72" @default.
• W2091218527 isParatext "false" @default.
• W2091218527 isRetracted "false" @default.
• W2091218527 magId "2091218527" @default.
• W2091218527 workType "article" @default.