FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091218752> ?p ?o ?g. }

• W2091218752 endingPage "265" @default.
• W2091218752 startingPage "258" @default.
• W2091218752 abstract "Membrane rafts may act as platforms for membrane protein signalling. Rafts have also been implicated in the sorting of membrane components during membrane budding. We have studied by fluorescence microscopy cross-linking of ganglioside GM1 in the human erythrocyte membrane, and how membrane proteins CD47 and CD59 distribute in GM1 patched discoid cells and calcium-induced echinocytic cells. Patching of ganglioside(M1) (GM1) by cholera toxin subunit B (CTB) plus anti-CTB resulted in the formation of usually 40-60 GM1 patches distributed over the membrane in discoid erythrocytes. Pre-treatment of erythrocytes with methyl-beta-cyclodextrin abolished GM1 patching. GM1 patching was insensitive to pre-fixation (paraformaldehyde) of cells. Patching of GM1 did not affect the discoid shape of erythrocytes. Membrane proteins CD47 and CD59 did not accumulate into GM1 patches. No capping of patches occurred. GM1 accumulated in calcium-induced echinocytic spiculae. Also CD59, but not CD47, accumulated in spiculae. However, CD59 showed a low degree of co-localization with GM1 and frequently accumulated in different spiculae than GM1. In conclusion, our study describes a novel method for examining properties and composition of rafts. The study characterizes raft patching in the human erythrocyte membrane and emphasizes the mobility and 'echinophilicity' of GM1. Glycosyl phosphatidylinositol-anchored CD59 was identified as a mobile 'echinophilic' but 'raftophobic(GM1)' protein. Largely immobile CD47 showed no segregation." @default.
• W2091218752 created "2016-06-24" @default.
• W2091218752 creator A5041098206 @default.
• W2091218752 creator A5074114013 @default.
• W2091218752 date "2008-01-01" @default.
• W2091218752 modified "2023-10-18" @default.
• W2091218752 title "Patching of ganglioside_M1in human erythrocytes – distribution of CD47 and CD59 in patched and curved membrane" @default.
• W2091218752 cites W1635401440 @default.
• W2091218752 cites W1898709484 @default.
• W2091218752 cites W1973791258 @default.
• W2091218752 cites W1973933701 @default.
• W2091218752 cites W1974926560 @default.
• W2091218752 cites W1977523984 @default.
• W2091218752 cites W1980334501 @default.
• W2091218752 cites W1988481644 @default.
• W2091218752 cites W1988530230 @default.
• W2091218752 cites W1992221541 @default.
• W2091218752 cites W1992868764 @default.
• W2091218752 cites W2000638372 @default.
• W2091218752 cites W2004296371 @default.
• W2091218752 cites W2010124864 @default.
• W2091218752 cites W2015716416 @default.
• W2091218752 cites W2026726527 @default.
• W2091218752 cites W2035810350 @default.
• W2091218752 cites W2037773086 @default.
• W2091218752 cites W2039348731 @default.
• W2091218752 cites W2039949492 @default.
• W2091218752 cites W2045537815 @default.
• W2091218752 cites W2048305330 @default.
• W2091218752 cites W2048887344 @default.
• W2091218752 cites W2051341804 @default.
• W2091218752 cites W2053046999 @default.
• W2091218752 cites W2053770297 @default.
• W2091218752 cites W2058235644 @default.
• W2091218752 cites W2064782071 @default.
• W2091218752 cites W2065730608 @default.
• W2091218752 cites W2071639848 @default.
• W2091218752 cites W2072384875 @default.
• W2091218752 cites W2084468460 @default.
• W2091218752 cites W2086358590 @default.
• W2091218752 cites W2086679183 @default.
• W2091218752 cites W2089988249 @default.
• W2091218752 cites W2099871325 @default.
• W2091218752 cites W2100826597 @default.
• W2091218752 cites W2101816342 @default.
• W2091218752 cites W2116856926 @default.
• W2091218752 cites W2128421163 @default.
• W2091218752 cites W2133788360 @default.
• W2091218752 cites W2136259733 @default.
• W2091218752 cites W2139846514 @default.
• W2091218752 cites W2143213067 @default.
• W2091218752 cites W2143983344 @default.
• W2091218752 cites W2148726513 @default.
• W2091218752 cites W2152506674 @default.
• W2091218752 cites W2163574066 @default.
• W2091218752 cites W2167486074 @default.
• W2091218752 doi "https://doi.org/10.1080/09687680802043638" @default.
• W2091218752 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18428041" @default.
• W2091218752 hasPublicationYear "2008" @default.
• W2091218752 type Work @default.
• W2091218752 sameAs 2091218752 @default.
• W2091218752 citedByCount "13" @default.
• W2091218752 countsByYear W20912187522012 @default.
• W2091218752 countsByYear W20912187522014 @default.
• W2091218752 countsByYear W20912187522015 @default.
• W2091218752 countsByYear W20912187522018 @default.
• W2091218752 crossrefType "journal-article" @default.
• W2091218752 hasAuthorship W2091218752A5041098206 @default.
• W2091218752 hasAuthorship W2091218752A5074114013 @default.
• W2091218752 hasBestOaLocation W20912187521 @default.
• W2091218752 hasConcept C111684460 @default.
• W2091218752 hasConcept C12554922 @default.
• W2091218752 hasConcept C142669718 @default.
• W2091218752 hasConcept C144647389 @default.
• W2091218752 hasConcept C1491633281 @default.
• W2091218752 hasConcept C159654299 @default.
• W2091218752 hasConcept C184404459 @default.
• W2091218752 hasConcept C185592680 @default.
• W2091218752 hasConcept C203014093 @default.
• W2091218752 hasConcept C2777006276 @default.
• W2091218752 hasConcept C2777331542 @default.
• W2091218752 hasConcept C41625074 @default.
• W2091218752 hasConcept C50244902 @default.
• W2091218752 hasConcept C55493867 @default.
• W2091218752 hasConcept C79266657 @default.
• W2091218752 hasConcept C86803240 @default.
• W2091218752 hasConcept C89423630 @default.
• W2091218752 hasConcept C95444343 @default.
• W2091218752 hasConceptScore W2091218752C111684460 @default.
• W2091218752 hasConceptScore W2091218752C12554922 @default.
• W2091218752 hasConceptScore W2091218752C142669718 @default.
• W2091218752 hasConceptScore W2091218752C144647389 @default.
• W2091218752 hasConceptScore W2091218752C1491633281 @default.
• W2091218752 hasConceptScore W2091218752C159654299 @default.
• W2091218752 hasConceptScore W2091218752C184404459 @default.
• W2091218752 hasConceptScore W2091218752C185592680 @default.
• W2091218752 hasConceptScore W2091218752C203014093 @default.
• W2091218752 hasConceptScore W2091218752C2777006276 @default.

• next