Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091224614> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2091224614 endingPage "1336" @default.
- W2091224614 startingPage "1329" @default.
- W2091224614 abstract "Abstract The proteins, DNA and RNA interaction networks govern various biological functions in living cells, these networks should be dynamically robust in the intracellular and environmental fluctuations. Here, we use Boolean network to study the robust structure of both genetic and logic networks. First, SOS network in bacteria E. coli, we find the signal-inhibitor (SIA) structure in transcription regulatory networks. Second, under the dynamical rule that inhibition is much stronger that activation, we haved searched 3-node non-self-loop logical networks that are dynamically robust, and that if the attractive basin of a final attractor is as seven, and the final attractor has only one active node, then the active node acts as inhibitor, and the SIA and signal-inhibitor (SI) structures are fundamental architectures of robust networks. SIA and SI networks with dynamic robustness against environment uncertainities may be selected and maintained over the course of evolution, rather than blind trial-error testing and being an accidental consequence of particular evolutionary history. SIA network can perform a more complex process than SI networks, and SIA might be used to design robust artificial genetic network. Our results provide dynamical support for why the inhibitors and SIA/SI structures are frequently employed in cellular regulatory networks." @default.
- W2091224614 created "2016-06-24" @default.
- W2091224614 creator A5039354723 @default.
- W2091224614 creator A5069265327 @default.
- W2091224614 date "2006-12-01" @default.
- W2091224614 modified "2023-09-27" @default.
- W2091224614 title "Genetic and logic networks with the signal-inhibitor-activator structure are dynamically robust" @default.
- W2091224614 cites W1497274060 @default.
- W2091224614 cites W1645305843 @default.
- W2091224614 cites W1971727132 @default.
- W2091224614 cites W1978486653 @default.
- W2091224614 cites W1985164652 @default.
- W2091224614 cites W1995907191 @default.
- W2091224614 cites W2038540528 @default.
- W2091224614 cites W2038696352 @default.
- W2091224614 cites W2039693330 @default.
- W2091224614 cites W2053961182 @default.
- W2091224614 cites W2076372398 @default.
- W2091224614 cites W2084554663 @default.
- W2091224614 cites W2142182986 @default.
- W2091224614 cites W3103071483 @default.
- W2091224614 doi "https://doi.org/10.1080/10020070612330149" @default.
- W2091224614 hasPublicationYear "2006" @default.
- W2091224614 type Work @default.
- W2091224614 sameAs 2091224614 @default.
- W2091224614 citedByCount "0" @default.
- W2091224614 crossrefType "journal-article" @default.
- W2091224614 hasAuthorship W2091224614A5039354723 @default.
- W2091224614 hasAuthorship W2091224614A5069265327 @default.
- W2091224614 hasConcept C104317684 @default.
- W2091224614 hasConcept C11413529 @default.
- W2091224614 hasConcept C134444547 @default.
- W2091224614 hasConcept C187455244 @default.
- W2091224614 hasConcept C41008148 @default.
- W2091224614 hasConcept C54355233 @default.
- W2091224614 hasConcept C63479239 @default.
- W2091224614 hasConcept C70721500 @default.
- W2091224614 hasConcept C86803240 @default.
- W2091224614 hasConceptScore W2091224614C104317684 @default.
- W2091224614 hasConceptScore W2091224614C11413529 @default.
- W2091224614 hasConceptScore W2091224614C134444547 @default.
- W2091224614 hasConceptScore W2091224614C187455244 @default.
- W2091224614 hasConceptScore W2091224614C41008148 @default.
- W2091224614 hasConceptScore W2091224614C54355233 @default.
- W2091224614 hasConceptScore W2091224614C63479239 @default.
- W2091224614 hasConceptScore W2091224614C70721500 @default.
- W2091224614 hasConceptScore W2091224614C86803240 @default.
- W2091224614 hasIssue "12" @default.
- W2091224614 hasLocation W20912246141 @default.
- W2091224614 hasOpenAccess W2091224614 @default.
- W2091224614 hasPrimaryLocation W20912246141 @default.
- W2091224614 hasRelatedWork W1481179460 @default.
- W2091224614 hasRelatedWork W184995394 @default.
- W2091224614 hasRelatedWork W2051213048 @default.
- W2091224614 hasRelatedWork W2137116076 @default.
- W2091224614 hasRelatedWork W2160562923 @default.
- W2091224614 hasRelatedWork W2248892376 @default.
- W2091224614 hasRelatedWork W2402814600 @default.
- W2091224614 hasRelatedWork W2404314426 @default.
- W2091224614 hasRelatedWork W2584455473 @default.
- W2091224614 hasRelatedWork W4239295757 @default.
- W2091224614 hasVolume "16" @default.
- W2091224614 isParatext "false" @default.
- W2091224614 isRetracted "false" @default.
- W2091224614 magId "2091224614" @default.
- W2091224614 workType "article" @default.