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- W2091233643 abstract "The Hytrosaviridae comprises a family of dsDNA viruses with a circular genome of 120–190 kbp. They are exclusively associated with Diptera, such as the tsetse fly, the house fly and the Narcissus bulb fly. Hytrosaviruses cause a very unique pathology including hypertrophy of salivary glands as well as testicular and ovarian malformation. On the other hand these viruses share a significant number of gene homologues with other dsDNA viruses, esp. baculoviruses and nudiviruses. These gene homologues include twelve so-called baculovirus core genes involved in transcription, DNA replication and the infection process. Most strikingly, the Musca domestica salivary gland hypertrophy virus (MdSGHV) encodes a homologue of a polyhedrin/granulin gene of Alpha-, Beta-, Gammabaculoviruses. Hence, it is proposed that hytrosaviruses are phylogenetically related to baculoviruses but evolved in a very close association with their dipteran hosts." @default.
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- W2091233643 date "2013-03-01" @default.
- W2091233643 modified "2023-09-24" @default.
- W2091233643 title "Phylogeny and evolution of Hytrosaviridae" @default.
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- W2091233643 doi "https://doi.org/10.1016/j.jip.2012.07.015" @default.
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