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- W2091236799 abstract "cessive amounts of amniotic fluid and normal urinary systems fails to support the view that these anomalies are secondary to compression. In a review of 38 cases of hypoplasia of the lung, Oyamada and associates 4 found only four with any abnormality of the extremities and none with camptodactyly and ankylosis. K~illdn and Winberg 5 found no instance of this combination of anomalies among 31 infants with pulmonary hypoplasia born in Sweden during the years 1965-1971. The unusual facies and flexion deformities of the hands are also seen in trisomy 18. We have seen one previable infant, born after 26 weeks' gestation, who had proved trisomy 18 and multiple anomalies including the triad of unusual facies, hypoplastic lungs, and arthrogryposis involving all four extremities. Microscopic sections of muscle showed focal areas of atrophy, identical with that seen in B. W. Absence of normal digital flexion creases is common in children with trisomy 18, reflecting the finger contractures present early in fetal development. Perhaps some of the infants who have been reported as instances of clinical trisomy 18 with normal chromosomes had this syndrome. Since each of our patients was a first-born infant, we have no information regarding etiology. The disorder need not be lethal at birth. In counseling parents of affected children, it is important to recognize that the full spectrum of the disorder is not known and that it may be compatible with continued life." @default.
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- W2091236799 date "1974-09-01" @default.
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- W2091236799 title "Pneumoperitoneum without gastrointestinal perforation in a neonate" @default.
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- W2091236799 doi "https://doi.org/10.1016/s0022-3476(74)80121-6" @default.
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