FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091239177> ?p ?o ?g. }

• W2091239177 endingPage "483" @default.
• W2091239177 startingPage "480" @default.
• W2091239177 abstract "Objectives To examine the cellular, plasma, and urinary oxalate and erythrocyte oxalate flux in patients with calcium oxalate monohydrate (COM) stone formation vs normal controls. Pathologic oxalate clearance in humans is mostly integrated in calcium oxalate stone formation. An underlying cause of deficient oxalate clearance could be defective transmembrane oxalate transport, which, in many tissues, is regulated by an anion exchanger (SLC26). Methods We studied 2 groups: 40 normal controls and 41 patients with COM stone formation. Red blood cells were divided for cellular oxalate measurement and for resuspension in a buffered solution (pH 7.40); 0.1 mmol/L oxalate was added. The supernatant was measured for oxalate immediately and 1 hour after incubation. The plasma and urinary oxalate were analyzed in parallel. Results The mean cellular oxalate concentrations were significantly greater in the normal controls (5.25 ± 0.47 μmol/L) than in those with COM stone formation (2.36 ± 0.28 μmol/L; P < .01). The mean urinary oxalate concentrations were significantly greater in those with COM stone formation (0.31 ± 0.02 mmol/L) than in the controls (0.24 ± 0.02 mmol/L; P < .01). The cellular oxalate concentrations correlated significantly with the plasma (r = 0.49-0.63; P < .01) and urinary oxalate (r = −0.29-0.41; P < .03) concentrations in both groups. The plasma oxalate concentrations correlated significantly with the urinary oxalate concentrations (r = −0.30; P < .03) in the controls and with the erythrocyte oxalate flux (r = 0.25; P < .05) in those with COM stone formation. Conclusions Our data implicate the presence of a cellular oxalate buffer to stabilize plasma and urinary oxalate concentrations in normal controls. To examine the cellular, plasma, and urinary oxalate and erythrocyte oxalate flux in patients with calcium oxalate monohydrate (COM) stone formation vs normal controls. Pathologic oxalate clearance in humans is mostly integrated in calcium oxalate stone formation. An underlying cause of deficient oxalate clearance could be defective transmembrane oxalate transport, which, in many tissues, is regulated by an anion exchanger (SLC26). We studied 2 groups: 40 normal controls and 41 patients with COM stone formation. Red blood cells were divided for cellular oxalate measurement and for resuspension in a buffered solution (pH 7.40); 0.1 mmol/L oxalate was added. The supernatant was measured for oxalate immediately and 1 hour after incubation. The plasma and urinary oxalate were analyzed in parallel. The mean cellular oxalate concentrations were significantly greater in the normal controls (5.25 ± 0.47 μmol/L) than in those with COM stone formation (2.36 ± 0.28 μmol/L; P < .01). The mean urinary oxalate concentrations were significantly greater in those with COM stone formation (0.31 ± 0.02 mmol/L) than in the controls (0.24 ± 0.02 mmol/L; P < .01). The cellular oxalate concentrations correlated significantly with the plasma (r = 0.49-0.63; P < .01) and urinary oxalate (r = −0.29-0.41; P < .03) concentrations in both groups. The plasma oxalate concentrations correlated significantly with the urinary oxalate concentrations (r = −0.30; P < .03) in the controls and with the erythrocyte oxalate flux (r = 0.25; P < .05) in those with COM stone formation. Our data implicate the presence of a cellular oxalate buffer to stabilize plasma and urinary oxalate concentrations in normal controls." @default.
• W2091239177 created "2016-06-24" @default.
• W2091239177 creator A5002773830 @default.
• W2091239177 creator A5017375379 @default.
• W2091239177 creator A5039027824 @default.
• W2091239177 creator A5039751847 @default.
• W2091239177 creator A5062251866 @default.
• W2091239177 creator A5062408272 @default.
• W2091239177 creator A5065289402 @default.
• W2091239177 date "2009-03-01" @default.
• W2091239177 modified "2023-09-27" @default.
• W2091239177 title "Role of Cellular Oxalate in Oxalate Clearance of Patients With Calcium Oxalate Monohydrate Stone Formation and Normal Controls" @default.
• W2091239177 cites W1987963142 @default.
• W2091239177 cites W2028294619 @default.
• W2091239177 cites W2060676126 @default.
• W2091239177 cites W2079688623 @default.
• W2091239177 cites W2084720244 @default.
• W2091239177 cites W2086439770 @default.
• W2091239177 cites W2087579719 @default.
• W2091239177 cites W2091180702 @default.
• W2091239177 cites W2093309797 @default.
• W2091239177 cites W2113263764 @default.
• W2091239177 cites W2123329701 @default.
• W2091239177 cites W2129652995 @default.
• W2091239177 doi "https://doi.org/10.1016/j.urology.2008.11.028" @default.
• W2091239177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19167040" @default.
• W2091239177 hasPublicationYear "2009" @default.
• W2091239177 type Work @default.
• W2091239177 sameAs 2091239177 @default.
• W2091239177 citedByCount "5" @default.
• W2091239177 countsByYear W20912391772014 @default.
• W2091239177 countsByYear W20912391772022 @default.
• W2091239177 crossrefType "journal-article" @default.
• W2091239177 hasAuthorship W2091239177A5002773830 @default.
• W2091239177 hasAuthorship W2091239177A5017375379 @default.
• W2091239177 hasAuthorship W2091239177A5039027824 @default.
• W2091239177 hasAuthorship W2091239177A5039751847 @default.
• W2091239177 hasAuthorship W2091239177A5062251866 @default.
• W2091239177 hasAuthorship W2091239177A5062408272 @default.
• W2091239177 hasAuthorship W2091239177A5065289402 @default.
• W2091239177 hasConcept C126322002 @default.
• W2091239177 hasConcept C134018914 @default.
• W2091239177 hasConcept C179104552 @default.
• W2091239177 hasConcept C185592680 @default.
• W2091239177 hasConcept C2776179656 @default.
• W2091239177 hasConcept C2776351790 @default.
• W2091239177 hasConcept C55493867 @default.
• W2091239177 hasConcept C71924100 @default.
• W2091239177 hasConcept C77411442 @default.
• W2091239177 hasConceptScore W2091239177C126322002 @default.
• W2091239177 hasConceptScore W2091239177C134018914 @default.
• W2091239177 hasConceptScore W2091239177C179104552 @default.
• W2091239177 hasConceptScore W2091239177C185592680 @default.
• W2091239177 hasConceptScore W2091239177C2776179656 @default.
• W2091239177 hasConceptScore W2091239177C2776351790 @default.
• W2091239177 hasConceptScore W2091239177C55493867 @default.
• W2091239177 hasConceptScore W2091239177C71924100 @default.
• W2091239177 hasConceptScore W2091239177C77411442 @default.
• W2091239177 hasIssue "3" @default.
• W2091239177 hasLocation W20912391771 @default.
• W2091239177 hasLocation W20912391772 @default.
• W2091239177 hasOpenAccess W2091239177 @default.
• W2091239177 hasPrimaryLocation W20912391771 @default.
• W2091239177 hasRelatedWork W1567106679 @default.
• W2091239177 hasRelatedWork W1982004379 @default.
• W2091239177 hasRelatedWork W2001654250 @default.
• W2091239177 hasRelatedWork W2038724580 @default.
• W2091239177 hasRelatedWork W2048103964 @default.
• W2091239177 hasRelatedWork W2050516444 @default.
• W2091239177 hasRelatedWork W2117259881 @default.
• W2091239177 hasRelatedWork W2155569180 @default.
• W2091239177 hasRelatedWork W2369595646 @default.
• W2091239177 hasRelatedWork W2389004481 @default.
• W2091239177 hasVolume "73" @default.
• W2091239177 isParatext "false" @default.
• W2091239177 isRetracted "false" @default.
• W2091239177 magId "2091239177" @default.
• W2091239177 workType "article" @default.