FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091245674> ?p ?o ?g. }

• W2091245674 endingPage "37" @default.
• W2091245674 startingPage "32" @default.
• W2091245674 abstract "The response of the systemic, pulmonary, hepatic and portal circulations to infusion of dopamine and epinephrine was studied in newborn piglets 1 to 3 d of age. Anesthetized animals were instrumented to measure cardiac index (CI), hepatic arterial flow, and portal venous blood flow. Catheters were inserted for measurement of systemic arterial pressure (SAP), pulmonary arterial pressure (PAP), and for sampling of arterial, portal venous, and mixed venous oxygen saturations and plasma lactate levels. Systemic, pulmonary and mesenteric vascular resistance indices (SVRI, PVRI, MVRI), and systemic and mesenteric oxygen extraction were calculated. Dopamine and epinephrine were infused in doses of 2, 10, 32 microg/kg/min and 0.2, 1.0, 3.2 microg/kg/min respectively, given in random order. Significant increases in SAP, PAP, and CI were demonstrated with 32 microg/kg/min of dopamine and the two higher doses (1.0 and 3.2 microg/kg/min) of epinephrine. There were no significant changes in SVRI and PVRI with dopamine infusions. Epinephrine at 3.2 microg/kg/min significantly elevated SVRI and PVRI. The SAP/PAP ratio was decreased with 32 microg/kg/min of dopamine whereas epinephrine did not affect the ratio. Dopamine had no significant effect on hepatic arterial flow, portal venous flow, or mesenteric vascular resistance. Epinephrine infusion at 3.2 microg/kg/min decreased portal venous blood flow, total hepatic blood flow, and hepatic oxygen delivery with an increase in calculated mesenteric vascular resistance. Systemic and mesenteric oxygen extraction were not affected by dopamine or epinephrine infusions. Plasma lactate levels were significantly elevated with epinephrine infusion 3.2 microg/kg/min. The differential responses of dopamine and epinephrine on pulmonary and mesenteric circulations may be significant in the pathophysiology and management of persistent fetal circulation and necrotizing enterocolitis." @default.
• W2091245674 created "2016-06-24" @default.
• W2091245674 creator A5007329349 @default.
• W2091245674 creator A5028307208 @default.
• W2091245674 creator A5029222734 @default.
• W2091245674 creator A5061786933 @default.
• W2091245674 creator A5065651735 @default.
• W2091245674 creator A5084450505 @default.
• W2091245674 date "1997-01-01" @default.
• W2091245674 modified "2023-09-27" @default.
• W2091245674 title "Systemic, pulmonary and mesenteric perfusion and oxygenation effects of dopamine and epinephrine." @default.
• W2091245674 cites W103661451 @default.
• W2091245674 cites W1498468770 @default.
• W2091245674 cites W16768731 @default.
• W2091245674 cites W1979606265 @default.
• W2091245674 cites W1979722576 @default.
• W2091245674 cites W1989507960 @default.
• W2091245674 cites W1990881511 @default.
• W2091245674 cites W1992216549 @default.
• W2091245674 cites W2031992185 @default.
• W2091245674 cites W2054241189 @default.
• W2091245674 cites W2055855202 @default.
• W2091245674 cites W2057282234 @default.
• W2091245674 cites W2076426690 @default.
• W2091245674 cites W2077262204 @default.
• W2091245674 cites W2087539833 @default.
• W2091245674 cites W2091002668 @default.
• W2091245674 cites W2224390479 @default.
• W2091245674 cites W2287328819 @default.
• W2091245674 cites W2341842259 @default.
• W2091245674 cites W2405831250 @default.
• W2091245674 cites W2412652449 @default.
• W2091245674 cites W2419363359 @default.
• W2091245674 cites W2436564899 @default.
• W2091245674 cites W2320786710 @default.
• W2091245674 doi "https://doi.org/10.1164/ajrccm.155.1.9001285" @default.
• W2091245674 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9001285" @default.
• W2091245674 hasPublicationYear "1997" @default.
• W2091245674 type Work @default.
• W2091245674 sameAs 2091245674 @default.
• W2091245674 citedByCount "54" @default.
• W2091245674 countsByYear W20912456742012 @default.
• W2091245674 countsByYear W20912456742014 @default.
• W2091245674 countsByYear W20912456742015 @default.
• W2091245674 countsByYear W20912456742016 @default.
• W2091245674 countsByYear W20912456742017 @default.
• W2091245674 countsByYear W20912456742018 @default.
• W2091245674 countsByYear W20912456742019 @default.
• W2091245674 countsByYear W20912456742020 @default.
• W2091245674 countsByYear W20912456742021 @default.
• W2091245674 countsByYear W20912456742022 @default.
• W2091245674 crossrefType "journal-article" @default.
• W2091245674 hasAuthorship W2091245674A5007329349 @default.
• W2091245674 hasAuthorship W2091245674A5028307208 @default.
• W2091245674 hasAuthorship W2091245674A5029222734 @default.
• W2091245674 hasAuthorship W2091245674A5061786933 @default.
• W2091245674 hasAuthorship W2091245674A5065651735 @default.
• W2091245674 hasAuthorship W2091245674A5084450505 @default.
• W2091245674 hasConcept C126322002 @default.
• W2091245674 hasConcept C178853913 @default.
• W2091245674 hasConcept C2775859304 @default.
• W2091245674 hasConcept C42219234 @default.
• W2091245674 hasConcept C58245268 @default.
• W2091245674 hasConcept C71924100 @default.
• W2091245674 hasConceptScore W2091245674C126322002 @default.
• W2091245674 hasConceptScore W2091245674C178853913 @default.
• W2091245674 hasConceptScore W2091245674C2775859304 @default.
• W2091245674 hasConceptScore W2091245674C42219234 @default.
• W2091245674 hasConceptScore W2091245674C58245268 @default.
• W2091245674 hasConceptScore W2091245674C71924100 @default.
• W2091245674 hasIssue "1" @default.
• W2091245674 hasLocation W20912456741 @default.
• W2091245674 hasLocation W20912456742 @default.
• W2091245674 hasOpenAccess W2091245674 @default.
• W2091245674 hasPrimaryLocation W20912456741 @default.
• W2091245674 hasRelatedWork W2004449713 @default.
• W2091245674 hasRelatedWork W2018306144 @default.
• W2091245674 hasRelatedWork W2026413826 @default.
• W2091245674 hasRelatedWork W2038512896 @default.
• W2091245674 hasRelatedWork W2040249177 @default.
• W2091245674 hasRelatedWork W2044985824 @default.
• W2091245674 hasRelatedWork W2134878907 @default.
• W2091245674 hasRelatedWork W2381946403 @default.
• W2091245674 hasRelatedWork W2460584456 @default.
• W2091245674 hasRelatedWork W59540023 @default.
• W2091245674 hasVolume "155" @default.
• W2091245674 isParatext "false" @default.
• W2091245674 isRetracted "false" @default.
• W2091245674 magId "2091245674" @default.
• W2091245674 workType "article" @default.