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- W2091253172 abstract "RATIONALE: Pediatric asthma prevalence varies dramatically (3-19%) among neighborhoods in New York City (NYC). We hypothesized that risks for asthma also vary among these neighborhoods. METHODS: Children from 3 groups participating in 2 studies were compared. NYC Neighborhood Asthma and Allergy case-control study recruited MIDDLE-INCOME children from the same employer-based health insurance who lived in low (LAPN) (Group A) and high (HAPN) (Group B) asthma prevalence neighborhoods. Columbia's Center for Children's Environmental Health birth cohort study recruited LOW-INCOME mothers living in HAPN (Group C). At age 7/8 years, children were classified as asthma cases or controls based on current symptoms and medication use. There were 64, 71 and 100 cases and 59, 53 and 180 controls in groups A, B, and C, respectively. Odds ratios (OR) were calculated by logistic regression, adjusting for ethnicity/race, sex and maternal asthma. Effect modification by study group (A,B,C) was tested using interaction terms to compare OR. RESULTS: There were several risks that differed between study groups. For example, reported household income was inversely associated with asthma in A (OR=0.84, P=0.032) but not in B (OR=0.94, P=0.48) or C (OR=1.01, P=0.85) (Pinteraction=0.025). Similarly, reported local drug dealer activity was associated with asthma in A but not in B or C (Pinteraction=0.002). Having an unmarried mother (Pinteraction=0.001) and reporting that the neighborhood was not a good place to raise children were significantly associated with asthma in B but not C (Pinteraction=0.014). CONCLUSIONS: Associations between demographic and social environment related risks and asthma differed by neighborhood and socio-economic status in NYC." @default.
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- W2091253172 date "2011-02-01" @default.
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- W2091253172 title "Risks for asthma at age 7 differ by neighborhood and socio-economic status in New York City" @default.
- W2091253172 doi "https://doi.org/10.1016/j.jaci.2010.12.693" @default.
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