FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091253248> ?p ?o ?g. }

• W2091253248 endingPage "3088" @default.
• W2091253248 startingPage "3085" @default.
• W2091253248 abstract "Abnormal tau cleavage is prominent in the neurofibrillary degeneration characteristic of Alzheimer's disease (AD) and related tauopathies. We recently showed that cleaved human tau is secreted by specific mechanisms when overexpressed. Here we examined the effect of expressing N‐terminal and full length tau constructs in transiently and stably transfected neuronal lines. We show that secreted tau exhibits a cleavage pattern similar to CSF‐tau from human AD patients and that tau secretion is specifically inhibited by the presence of the exon 2 insert. These results suggest that tau secretion may play a hitherto unsuspected role in AD and related tauopathies." @default.
• W2091253248 created "2016-06-24" @default.
• W2091253248 creator A5010189286 @default.
• W2091253248 creator A5012105133 @default.
• W2091253248 creator A5021545209 @default.
• W2091253248 date "2010-05-27" @default.
• W2091253248 modified "2023-10-18" @default.
• W2091253248 title "Secretion of human tau fragments resembling CSF‐tau in Alzheimer's disease is modulated by the presence of the exon 2 insert" @default.
• W2091253248 cites W1521316141 @default.
• W2091253248 cites W1561023982 @default.
• W2091253248 cites W1968372370 @default.
• W2091253248 cites W1978012364 @default.
• W2091253248 cites W1984496263 @default.
• W2091253248 cites W1984770038 @default.
• W2091253248 cites W1989208474 @default.
• W2091253248 cites W1997942761 @default.
• W2091253248 cites W2000655392 @default.
• W2091253248 cites W2010781827 @default.
• W2091253248 cites W2017064090 @default.
• W2091253248 cites W2034332531 @default.
• W2091253248 cites W2072850679 @default.
• W2091253248 cites W2075560127 @default.
• W2091253248 cites W2084009738 @default.
• W2091253248 cites W2092245599 @default.
• W2091253248 cites W2099340107 @default.
• W2091253248 cites W2125172225 @default.
• W2091253248 cites W2130446116 @default.
• W2091253248 cites W2137176838 @default.
• W2091253248 cites W2154665893 @default.
• W2091253248 cites W2159643400 @default.
• W2091253248 cites W2295393683 @default.
• W2091253248 cites W43861046 @default.
• W2091253248 doi "https://doi.org/10.1016/j.febslet.2010.05.042" @default.
• W2091253248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20553717" @default.
• W2091253248 hasPublicationYear "2010" @default.
• W2091253248 type Work @default.
• W2091253248 sameAs 2091253248 @default.
• W2091253248 citedByCount "79" @default.
• W2091253248 countsByYear W20912532482012 @default.
• W2091253248 countsByYear W20912532482013 @default.
• W2091253248 countsByYear W20912532482014 @default.
• W2091253248 countsByYear W20912532482015 @default.
• W2091253248 countsByYear W20912532482016 @default.
• W2091253248 countsByYear W20912532482017 @default.
• W2091253248 countsByYear W20912532482018 @default.
• W2091253248 countsByYear W20912532482019 @default.
• W2091253248 countsByYear W20912532482020 @default.
• W2091253248 countsByYear W20912532482021 @default.
• W2091253248 countsByYear W20912532482022 @default.
• W2091253248 countsByYear W20912532482023 @default.
• W2091253248 crossrefType "journal-article" @default.
• W2091253248 hasAuthorship W2091253248A5010189286 @default.
• W2091253248 hasAuthorship W2091253248A5012105133 @default.
• W2091253248 hasAuthorship W2091253248A5021545209 @default.
• W2091253248 hasBestOaLocation W20912532481 @default.
• W2091253248 hasConcept C104317684 @default.
• W2091253248 hasConcept C126322002 @default.
• W2091253248 hasConcept C134018914 @default.
• W2091253248 hasConcept C151730666 @default.
• W2091253248 hasConcept C153911025 @default.
• W2091253248 hasConcept C169760540 @default.
• W2091253248 hasConcept C175156509 @default.
• W2091253248 hasConcept C185592680 @default.
• W2091253248 hasConcept C2777670902 @default.
• W2091253248 hasConcept C2778670691 @default.
• W2091253248 hasConcept C2779134260 @default.
• W2091253248 hasConcept C3017833866 @default.
• W2091253248 hasConcept C36823959 @default.
• W2091253248 hasConcept C43369102 @default.
• W2091253248 hasConcept C49039625 @default.
• W2091253248 hasConcept C502032728 @default.
• W2091253248 hasConcept C54009773 @default.
• W2091253248 hasConcept C54355233 @default.
• W2091253248 hasConcept C55493867 @default.
• W2091253248 hasConcept C71924100 @default.
• W2091253248 hasConcept C81885089 @default.
• W2091253248 hasConcept C86803240 @default.
• W2091253248 hasConcept C95444343 @default.
• W2091253248 hasConceptScore W2091253248C104317684 @default.
• W2091253248 hasConceptScore W2091253248C126322002 @default.
• W2091253248 hasConceptScore W2091253248C134018914 @default.
• W2091253248 hasConceptScore W2091253248C151730666 @default.
• W2091253248 hasConceptScore W2091253248C153911025 @default.
• W2091253248 hasConceptScore W2091253248C169760540 @default.
• W2091253248 hasConceptScore W2091253248C175156509 @default.
• W2091253248 hasConceptScore W2091253248C185592680 @default.
• W2091253248 hasConceptScore W2091253248C2777670902 @default.
• W2091253248 hasConceptScore W2091253248C2778670691 @default.
• W2091253248 hasConceptScore W2091253248C2779134260 @default.
• W2091253248 hasConceptScore W2091253248C3017833866 @default.
• W2091253248 hasConceptScore W2091253248C36823959 @default.
• W2091253248 hasConceptScore W2091253248C43369102 @default.
• W2091253248 hasConceptScore W2091253248C49039625 @default.
• W2091253248 hasConceptScore W2091253248C502032728 @default.
• W2091253248 hasConceptScore W2091253248C54009773 @default.
• W2091253248 hasConceptScore W2091253248C54355233 @default.
• W2091253248 hasConceptScore W2091253248C55493867 @default.
• W2091253248 hasConceptScore W2091253248C71924100 @default.

• next