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- W2091259680 abstract "The neuronal presynaptic membrane t-SNARE complex consists of the transmembrane protein syntaxin with the palmitoylated protein SNAP-25. In non-neuronal tissues, SNAP-23 replaces SNAP-25 in the t-SNARE complex, although the mechanism of membrane anchoring of SNAP-23 has not been determined. We now report that like SNAP-25, SNAP-23 is palmitoylatedin vivoon one or more cysteine residues present in a central “palmitoylation domain.” Interestingly, SNAP-23 is palmitoylated less well than SNAP-25, andin vivobinding studies indicate a correlation between the extent of palmitoylation and the ability of SNAP-23 or SNAP-25 to bind to syntaxinin vivo." @default.
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- W2091259680 date "1999-05-01" @default.
- W2091259680 modified "2023-09-27" @default.
- W2091259680 title "SNAP-23 and SNAP-25 Are Palmitoylatedin Vivo" @default.
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- W2091259680 doi "https://doi.org/10.1006/bbrc.1999.0652" @default.
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