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- W2091264304 abstract "Abstract Sera collected from patients with acute hepatitis A virus (HAV) infection and convalescent sera were examined for cytolytic activity against HAV‐infected human‐embryo lung fibroblasts (HAV carrier fibroblasts). Using the 51 chromium release assay, no complement dependent antibody mediated cytolytic activity against HAV carrier cells could be detected. In control experiments with identical cell strains, anti‐herpes simplex virus (HSV) positive sera and complement caused specific lysis of HSV type 1 infected target cells. The data presented here do not support the hypothesis that in the possible immunopathogenesis of HAV infection, complement‐dependent cytolytic antibodies play an essential role." @default.
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- W2091264304 date "1986-09-01" @default.
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- W2091264304 title "Lack of Complement-Dependent Cytolytic Antibodies in Hepatitis A Virus Infection" @default.
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- W2091264304 doi "https://doi.org/10.1002/jmv.1890200105" @default.
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