Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091270097> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2091270097 endingPage "63" @default.
- W2091270097 startingPage "57" @default.
- W2091270097 abstract "Our previous studies have shown that leukotriene (LT) and platelet activating factor (PAF) are important inflammatory mediators (IMs) in the pathogenesis of otitis media with effusion (OME). The purpose of this study was to determine the effect of a LT-inhibitor and/or PAF-antagonist on experimentally induced OME by killed H. influenzae in chinchillas. LT-inhibitor SCH-37224 and/or PAF-antagonist WEB-2170 were systematically administered, each separately or in combination, 2h prior and then at regular intervals after the injection of killed H. influenzae into the superior bullae. After 48h, OME was completely prevented in the combination group while it was only partially prevented in the other two separately treated groups. Animals in the control group all developed OME. Findings of this study suggest the importance of LT and PAF in the pathogenesis of OME and the usefulness of their blockers in the prevention of OME suggesting possible future therapeutic implication." @default.
- W2091270097 created "2016-06-24" @default.
- W2091270097 creator A5062490835 @default.
- W2091270097 creator A5069514415 @default.
- W2091270097 creator A5085847124 @default.
- W2091270097 date "2004-01-01" @default.
- W2091270097 modified "2023-09-26" @default.
- W2091270097 title "Effect of inhibitors of leukotriene and/or platelet activating factor on killed H. influenzae induced experimental otitis media with effusion" @default.
- W2091270097 cites W1990167531 @default.
- W2091270097 cites W2044290794 @default.
- W2091270097 cites W2054946013 @default.
- W2091270097 cites W2066192340 @default.
- W2091270097 cites W2079376305 @default.
- W2091270097 cites W2100439414 @default.
- W2091270097 cites W2171030028 @default.
- W2091270097 cites W2312530196 @default.
- W2091270097 cites W2320115908 @default.
- W2091270097 cites W2334671521 @default.
- W2091270097 cites W2335307466 @default.
- W2091270097 cites W2406280347 @default.
- W2091270097 doi "https://doi.org/10.1016/j.ijporl.2003.09.006" @default.
- W2091270097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14687688" @default.
- W2091270097 hasPublicationYear "2004" @default.
- W2091270097 type Work @default.
- W2091270097 sameAs 2091270097 @default.
- W2091270097 citedByCount "6" @default.
- W2091270097 countsByYear W20912700972016 @default.
- W2091270097 countsByYear W20912700972018 @default.
- W2091270097 crossrefType "journal-article" @default.
- W2091270097 hasAuthorship W2091270097A5062490835 @default.
- W2091270097 hasAuthorship W2091270097A5069514415 @default.
- W2091270097 hasAuthorship W2091270097A5085847124 @default.
- W2091270097 hasConcept C126322002 @default.
- W2091270097 hasConcept C141071460 @default.
- W2091270097 hasConcept C163430725 @default.
- W2091270097 hasConcept C170493617 @default.
- W2091270097 hasConcept C203014093 @default.
- W2091270097 hasConcept C2776042228 @default.
- W2091270097 hasConcept C2776439223 @default.
- W2091270097 hasConcept C2776452501 @default.
- W2091270097 hasConcept C2776885963 @default.
- W2091270097 hasConcept C2777242621 @default.
- W2091270097 hasConcept C2779020240 @default.
- W2091270097 hasConcept C2780942790 @default.
- W2091270097 hasConcept C71924100 @default.
- W2091270097 hasConcept C98274493 @default.
- W2091270097 hasConceptScore W2091270097C126322002 @default.
- W2091270097 hasConceptScore W2091270097C141071460 @default.
- W2091270097 hasConceptScore W2091270097C163430725 @default.
- W2091270097 hasConceptScore W2091270097C170493617 @default.
- W2091270097 hasConceptScore W2091270097C203014093 @default.
- W2091270097 hasConceptScore W2091270097C2776042228 @default.
- W2091270097 hasConceptScore W2091270097C2776439223 @default.
- W2091270097 hasConceptScore W2091270097C2776452501 @default.
- W2091270097 hasConceptScore W2091270097C2776885963 @default.
- W2091270097 hasConceptScore W2091270097C2777242621 @default.
- W2091270097 hasConceptScore W2091270097C2779020240 @default.
- W2091270097 hasConceptScore W2091270097C2780942790 @default.
- W2091270097 hasConceptScore W2091270097C71924100 @default.
- W2091270097 hasConceptScore W2091270097C98274493 @default.
- W2091270097 hasIssue "1" @default.
- W2091270097 hasLocation W20912700971 @default.
- W2091270097 hasLocation W20912700972 @default.
- W2091270097 hasOpenAccess W2091270097 @default.
- W2091270097 hasPrimaryLocation W20912700971 @default.
- W2091270097 hasRelatedWork W1775467750 @default.
- W2091270097 hasRelatedWork W1974285777 @default.
- W2091270097 hasRelatedWork W1974786438 @default.
- W2091270097 hasRelatedWork W1983741531 @default.
- W2091270097 hasRelatedWork W1984662841 @default.
- W2091270097 hasRelatedWork W2091270097 @default.
- W2091270097 hasRelatedWork W2160412140 @default.
- W2091270097 hasRelatedWork W2312530196 @default.
- W2091270097 hasRelatedWork W2339385067 @default.
- W2091270097 hasRelatedWork W2354426633 @default.
- W2091270097 hasVolume "68" @default.
- W2091270097 isParatext "false" @default.
- W2091270097 isRetracted "false" @default.
- W2091270097 magId "2091270097" @default.
- W2091270097 workType "article" @default.