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- W2091275170 abstract "A Cre recombinase expression cassette was inserted into the X-linked Hprt locus by gene targeting in a mouse embryonic stem (ES) cell line isogenic to strain 129S1/SvImJ (129S1), then the transgene was introduced into 129S1 mice through ES cell chimeras. When females hemizygous for this transgene were mated to males carrying a neomycin selection cassette flanked by loxP sites, the cassette was always excised regardless of Cre inheritance and without detectable mosaicism. The usefulness of this Cre-deleter transgenic line is in its efficiency and defined genetic status in terms of mouse strain and location of the transgene." @default.
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- W2091275170 date "2002-03-01" @default.
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- W2091275170 title "A cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ" @default.
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- W2091275170 doi "https://doi.org/10.1002/gene.10030" @default.
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