Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091275649> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W2091275649 abstract "The presence of macroamylasemia can be suspected when a patient has low renal clearance of amylase relative to creatinine (Cam/Ccr). However, the Cam/Ccr is seldom reduced to the extent expected given the fraction of amylase that appears to be bound in the macroamylase complex by gel filtration studies at 3 degrees C. Therefore, we tested the possibility that the binding of amylase in macroamylase complexes was temperature dependent and that binding at physiological temperatures might be less than at 3 degrees C. Gel filtration of five macroamylase-containing sera was carried out at temperatures of 3 degrees, 25 degrees, 37 degrees, 43 degrees, and 49 degrees C. Binding of amylase in the complex decreased as the temperature increased with virtually all amylase bound at 3 degrees C and virtually no amylase bound at 49 degrees C. The fraction of the amylase that bound at 37 degrees C was approximately what would have been predicted from the Cam/Ccr of each of the five subjects. We conclude that amylase binding in macroamylase complexes is extremely temperature sensitive and appreciable changes in binding may occur over the physiological temperature range of 37-41 degrees C." @default.
- W2091275649 created "2016-06-24" @default.
- W2091275649 creator A5048218266 @default.
- W2091275649 creator A5060886793 @default.
- W2091275649 creator A5062815441 @default.
- W2091275649 date "1987-01-01" @default.
- W2091275649 modified "2023-09-23" @default.
- W2091275649 title "Temperature Dependence of Macroamylase Binding" @default.
- W2091275649 doi "https://doi.org/10.1097/00006676-198701000-00008" @default.
- W2091275649 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2437572" @default.
- W2091275649 hasPublicationYear "1987" @default.
- W2091275649 type Work @default.
- W2091275649 sameAs 2091275649 @default.
- W2091275649 citedByCount "1" @default.
- W2091275649 crossrefType "journal-article" @default.
- W2091275649 hasAuthorship W2091275649A5048218266 @default.
- W2091275649 hasAuthorship W2091275649A5060886793 @default.
- W2091275649 hasAuthorship W2091275649A5062815441 @default.
- W2091275649 hasConcept C107824862 @default.
- W2091275649 hasConcept C149629883 @default.
- W2091275649 hasConcept C170835558 @default.
- W2091275649 hasConcept C181199279 @default.
- W2091275649 hasConcept C185592680 @default.
- W2091275649 hasConcept C193363816 @default.
- W2091275649 hasConcept C43617362 @default.
- W2091275649 hasConcept C55493867 @default.
- W2091275649 hasConcept C8010536 @default.
- W2091275649 hasConceptScore W2091275649C107824862 @default.
- W2091275649 hasConceptScore W2091275649C149629883 @default.
- W2091275649 hasConceptScore W2091275649C170835558 @default.
- W2091275649 hasConceptScore W2091275649C181199279 @default.
- W2091275649 hasConceptScore W2091275649C185592680 @default.
- W2091275649 hasConceptScore W2091275649C193363816 @default.
- W2091275649 hasConceptScore W2091275649C43617362 @default.
- W2091275649 hasConceptScore W2091275649C55493867 @default.
- W2091275649 hasConceptScore W2091275649C8010536 @default.
- W2091275649 hasLocation W20912756491 @default.
- W2091275649 hasLocation W20912756492 @default.
- W2091275649 hasOpenAccess W2091275649 @default.
- W2091275649 hasPrimaryLocation W20912756491 @default.
- W2091275649 hasRelatedWork W1528249941 @default.
- W2091275649 hasRelatedWork W1975032327 @default.
- W2091275649 hasRelatedWork W2026187888 @default.
- W2091275649 hasRelatedWork W2043883659 @default.
- W2091275649 hasRelatedWork W2088905508 @default.
- W2091275649 hasRelatedWork W2095015573 @default.
- W2091275649 hasRelatedWork W2095061672 @default.
- W2091275649 hasRelatedWork W2613982790 @default.
- W2091275649 hasRelatedWork W2940733281 @default.
- W2091275649 hasRelatedWork W54282416 @default.
- W2091275649 isParatext "false" @default.
- W2091275649 isRetracted "false" @default.
- W2091275649 magId "2091275649" @default.
- W2091275649 workType "article" @default.