Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091285705> ?p ?o ?g. }
- W2091285705 endingPage "692" @default.
- W2091285705 startingPage "681" @default.
- W2091285705 abstract "The mechanism of T cell receptor signaling is unclear. Included among models for TCR signaling is ligand-induced oligomerization in a fashion analogous to other cell surface receptors. Published kinetic, saturation binding, and light scattering experiments have been interpreted to suggest a propensity for soluble αβTCR/peptide/MHC ectodomain complexes to oligomerize. Upon performing these experiments with soluble ectodomains of human class I and class II restricted αβTCRs, we find no evidence for dimerization or oligomerization of complexes. Apparently, oligomerization in solution to a detectable extent is not a general property of soluble αβTCRs or their complexes with ligand. Our results suggest that membrane-anchored, fully assembled TCRs should be studied to determine the role oligomerization plays in T cell signaling." @default.
- W2091285705 created "2016-06-24" @default.
- W2091285705 creator A5010803082 @default.
- W2091285705 creator A5082462618 @default.
- W2091285705 date "2001-06-01" @default.
- W2091285705 modified "2023-10-18" @default.
- W2091285705 title "αβ T Cell Receptor Ligand-Specific Oligomerization Revisited" @default.
- W2091285705 cites W1519533633 @default.
- W2091285705 cites W1525871963 @default.
- W2091285705 cites W1562441478 @default.
- W2091285705 cites W1622169185 @default.
- W2091285705 cites W1855822212 @default.
- W2091285705 cites W1971178765 @default.
- W2091285705 cites W1985349820 @default.
- W2091285705 cites W1995138538 @default.
- W2091285705 cites W1995269556 @default.
- W2091285705 cites W1995925083 @default.
- W2091285705 cites W2003986211 @default.
- W2091285705 cites W2007211891 @default.
- W2091285705 cites W2014326164 @default.
- W2091285705 cites W2017507133 @default.
- W2091285705 cites W2019047500 @default.
- W2091285705 cites W2021010454 @default.
- W2091285705 cites W2021922884 @default.
- W2091285705 cites W2025476985 @default.
- W2091285705 cites W2025783409 @default.
- W2091285705 cites W2028104451 @default.
- W2091285705 cites W2038707726 @default.
- W2091285705 cites W2043080692 @default.
- W2091285705 cites W2047357490 @default.
- W2091285705 cites W2047784800 @default.
- W2091285705 cites W2063333925 @default.
- W2091285705 cites W2063711348 @default.
- W2091285705 cites W2066860834 @default.
- W2091285705 cites W2067353129 @default.
- W2091285705 cites W2070921472 @default.
- W2091285705 cites W2071423255 @default.
- W2091285705 cites W2075705506 @default.
- W2091285705 cites W2077438903 @default.
- W2091285705 cites W2077864494 @default.
- W2091285705 cites W2080956086 @default.
- W2091285705 cites W2089666002 @default.
- W2091285705 cites W2106856156 @default.
- W2091285705 cites W2119527055 @default.
- W2091285705 cites W2139823369 @default.
- W2091285705 cites W2150345297 @default.
- W2091285705 cites W2155740919 @default.
- W2091285705 cites W2159756478 @default.
- W2091285705 cites W2170820778 @default.
- W2091285705 doi "https://doi.org/10.1016/s1074-7613(01)00160-1" @default.
- W2091285705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11420039" @default.
- W2091285705 hasPublicationYear "2001" @default.
- W2091285705 type Work @default.
- W2091285705 sameAs 2091285705 @default.
- W2091285705 citedByCount "44" @default.
- W2091285705 countsByYear W20912857052012 @default.
- W2091285705 countsByYear W20912857052013 @default.
- W2091285705 countsByYear W20912857052014 @default.
- W2091285705 countsByYear W20912857052018 @default.
- W2091285705 countsByYear W20912857052021 @default.
- W2091285705 crossrefType "journal-article" @default.
- W2091285705 hasAuthorship W2091285705A5010803082 @default.
- W2091285705 hasAuthorship W2091285705A5082462618 @default.
- W2091285705 hasBestOaLocation W20912857051 @default.
- W2091285705 hasConcept C1009742 @default.
- W2091285705 hasConcept C116569031 @default.
- W2091285705 hasConcept C12554922 @default.
- W2091285705 hasConcept C1491633281 @default.
- W2091285705 hasConcept C170493617 @default.
- W2091285705 hasConcept C19317047 @default.
- W2091285705 hasConcept C203014093 @default.
- W2091285705 hasConcept C2776090121 @default.
- W2091285705 hasConcept C2778106830 @default.
- W2091285705 hasConcept C55493867 @default.
- W2091285705 hasConcept C62478195 @default.
- W2091285705 hasConcept C86803240 @default.
- W2091285705 hasConcept C8891405 @default.
- W2091285705 hasConcept C95444343 @default.
- W2091285705 hasConceptScore W2091285705C1009742 @default.
- W2091285705 hasConceptScore W2091285705C116569031 @default.
- W2091285705 hasConceptScore W2091285705C12554922 @default.
- W2091285705 hasConceptScore W2091285705C1491633281 @default.
- W2091285705 hasConceptScore W2091285705C170493617 @default.
- W2091285705 hasConceptScore W2091285705C19317047 @default.
- W2091285705 hasConceptScore W2091285705C203014093 @default.
- W2091285705 hasConceptScore W2091285705C2776090121 @default.
- W2091285705 hasConceptScore W2091285705C2778106830 @default.
- W2091285705 hasConceptScore W2091285705C55493867 @default.
- W2091285705 hasConceptScore W2091285705C62478195 @default.
- W2091285705 hasConceptScore W2091285705C86803240 @default.
- W2091285705 hasConceptScore W2091285705C8891405 @default.
- W2091285705 hasConceptScore W2091285705C95444343 @default.
- W2091285705 hasIssue "6" @default.
- W2091285705 hasLocation W20912857051 @default.
- W2091285705 hasLocation W20912857052 @default.
- W2091285705 hasOpenAccess W2091285705 @default.
- W2091285705 hasPrimaryLocation W20912857051 @default.
- W2091285705 hasRelatedWork W104003022 @default.