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- W2091287802 abstract "This study investigated the influence on ventilation of elevated CO2 in the nasal and buccal cavities (NaBuCO2) vs the effect of elevated CO2 levels inspired into the lungs (LuCO2). Separate gas sources were used to independent alter NaBuCo2 and LuCo2. As little as 1% NaBuCO2 or LuCO2 significantly increased the pause duration between the active expiratory-inspiratory cycles. Elevated NaBuCO2 caused minor changes in tidal volume, mean inspiratory and expiratory flow, and inspiratory and expiratory durations with a significant reduction in total ventilation. Elevated LuCO2 had little effect on inspiratory or expiratory durations but unlike CO2 in the upper airways, significantly increased tidal volume and mean inspiratory and expiratory flows. This study demonstrates that the increased pause duration seen in the tegu lizard to elevated environmental CO2 is due to a receptor response in the buccal or nasal cavities and also to elevated CO2 concetrations inpired into the lungs. Sensitivity of the ventilatory response to CO2 in the upper airways is well within a physiologically relevant range." @default.
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- W2091287802 date "1985-12-01" @default.
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- W2091287802 title "Breathing response of the tegu lizard to 1–4% CO2 in the mouth and nose or inspired into the lungs" @default.
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- W2091287802 doi "https://doi.org/10.1016/0034-5687(85)90092-1" @default.
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