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- W2091288150 abstract "In a recent issue of Nutrition, Metabolism & Cardiovascular Diseases, we read with great interest the published article by Baragetti et al. entitled with “Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general population” [ [1] Baragetti A. Knoflach M. Cuccovillo I. Grigore L. Casula M. Garlaschelli K.J. et al. Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general population. Nutr Metab Cardiovasc Dis. 2014; 24: 518-523 Abstract Full Text Full Text PDF PubMed Scopus (27) Google Scholar ]. This prospective study is important because it provides scientific information on this clinically relevant condition. They have discussed that PTX-3 may have a role on predicting the progression of common carotid artery intima media thickness in the general population during 5 or 6 years of follow-up. Then they concluded that PTX3 plasma level was neither an independent predictor of progression of subclinical atherosclerosis in different arterial territories, including carotid and femoral arteries nor of incident cardiovascular events. However, there are some points that need to be clarified. Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general populationNutrition, Metabolism and Cardiovascular DiseasesVol. 24Issue 5PreviewPentraxin 3 (PTX3) is an essential component of the humoral arm of innate immunity and, like C-reactive protein, is independently associated with the risk of developing vascular events. Aim of this study was to investigate, in two large population-based surveys, the Bruneck Study and the PLIC Study, whether PTX3 plasma levels predict the progression of common carotid artery intima–media thickness (CCA-IMT), a surrogate marker of atherosclerosis, in the general population during 5 or 6 years of follow-up. Full-Text PDF" @default.
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- W2091288150 date "2014-12-01" @default.
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- W2091288150 title "Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general population: A methodological approach" @default.
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- W2091288150 doi "https://doi.org/10.1016/j.numecd.2014.08.011" @default.
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