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- W2091288418 abstract "The patterns of laminin A, B1, B2, nidogen and collagen α1(IV) gene expression in the embryonic mouse lung were determined using in situ hybridization histochemistry at a stage when branching morphogenesis is taking place. Collagen α1(IV), laminin B1 and B2 genes were expressed throughout the mesenchyme and epithelium. Nidogen gene expression was uniform throughout the mesenchyme but was not detected in epithelial cells. Laminin A mRNA was localized to cells closely associated with a basement membrane at the epithelial-mesenchymal interface. However, expression of the laminin A gene was limited to the mesenchymal cells in bronchial regions and to epithelial cells in distal terminal lobules. We propose that the pattern of laminin A gene expression in different regions of the developing lung will influence the structure of the basement membrane at the epithelial-mesenchymal interface and thus have a role in branching morphogenesis." @default.
- W2091288418 created "2016-06-24" @default.
- W2091288418 creator A5058024376 @default.
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- W2091288418 date "1994-03-01" @default.
- W2091288418 modified "2023-09-26" @default.
- W2091288418 title "Expression of collagen α1(IV), laminin and nidogen genes in the embryonic mouse lung: implications for branching morphogenesis" @default.
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- W2091288418 doi "https://doi.org/10.1016/0925-4773(94)90007-8" @default.
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