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- W2091288993 abstract "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a familial vascular disorder associated with migraines, recurrent ischemic strokes, and early-onset multiinfarct dementia. The diagnosis of CADASIL is made ultrastructurally by finding characteristic granular, electron-dense, osmiophilic material attached to vascular smooth muscle cells. These changes have been found in brain, skeletal muscle, nerve, and skin. We describe a woman with CADASIL diagnosed on the basis of brain and skin electronmicroscopic findings. Dermatologists and dermatopathologists need to be aware of this disorder because characteristic electronmicroscopic changes on a skin biopsy specimen are diagnostic." @default.
- W2091288993 created "2016-06-24" @default.
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- W2091288993 date "2000-12-01" @default.
- W2091288993 modified "2023-10-18" @default.
- W2091288993 title "CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy): Diagnostic skin biopsy changes determined by electron microscopy" @default.
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- W2091288993 doi "https://doi.org/10.1067/mjd.2000.110895" @default.
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