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- W2091289102 abstract "Abstract A cytological analysis of serially sectioned unpenetrated and penetrated mouse eggs revealed the existence of a marked polarity in the distribution of cortical granules and of microvilli in the egg cortex. Approximately 20% of the total cortex homolateral to the meiotic spindle was totally devoid of cortical granules and was covered by a smooth oolemma which appeared uncapable of binding capacitated epididymal spermatozoa. In the remaining 80% of the egg, the cortex contained a heterogeneous population of cortical granules and was covered by short microvilli; sperm penetration of the mouse vitellus was restricted to this area. Quantitative estimates of cortical granule complements in eggs before (0 and 30 min), during (60 min), and after (60 and 120 min) sperm-egg fusion indicated that approximately 25% of the granules were released by exocytosis within the initial 30 min of insemination. No functional significance could, however, be attributed to such a premature release, since the fertilizability of eggs with reduced cortical granule complements was not affected." @default.
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- W2091289102 date "1977-05-01" @default.
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- W2091289102 title "Cortical granule distribution and cell surface characteristics in mouse eggs" @default.
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- W2091289102 doi "https://doi.org/10.1016/0012-1606(77)90354-2" @default.
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