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- W2091298509 abstract "The elaboration of cell form has fascinated biologists for generations. A vast body of literature details the life cycles, anatomy, and developmental programs of many species. The mechanisms responsible for the observed diversity of structure involve polarization, directed growth, and spatial memory. These issues of morphogenesis are currently under study in the budding yeast Saccharomyces cerevisiae and other fungi. In yeast, a number of genes are known that specifically affect either the orientation or the assembly of a polarity axis. These include the bud-site selection genes, BUD1–BUD5, as well as the polarity establishment genes, CDC24, CDC42, CDC43, and BEM1. Members of each of these classes encode elements in signal transduction type pathways. This review examines our present understanding of the molecular machinery responsible for orienting and assembling cell polarity as best understood in S. cerevisiae, and speculates about how similar machinery might function in other fungi. Key words: morphogenesis, polarity, yeast, Saccharomyces, development." @default.
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- W2091298509 date "1995-12-31" @default.
- W2091298509 modified "2023-09-26" @default.
- W2091298509 title "The shape of things to come: morphogenesis in yeast and related patterns in other systems" @default.
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- W2091298509 doi "https://doi.org/10.1139/b95-252" @default.
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