FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091325241> ?p ?o ?g. }

• W2091325241 endingPage "23" @default.
• W2091325241 startingPage "12" @default.
• W2091325241 abstract "Zygotic transcription was analyzed in embryos of the glossiphoniid leech Helobdella triserialis by autoradiographic detection of tritiated uridine incorporated in the presence or absence of low concentrations of alpha-amanitin. RNA synthesis was first detected after the second cleavage and alpha-amanitin-sensitive RNA synthesis was first detected during the divisions yielding the embryonic stem cells, or teloblasts. RNA synthesis increased as development progressed, and the bulk of alpha-amanitin-sensitive RNA synthesis was found in two classes of cells, the blast cells, which are the progeny of the teloblasts, and the micromere-derived cells. The time during which zygotic gene products are required was determined by observing the developmental consequences of alpha-amanitin exposure. Zygotes microinjected with alpha-amanitin underwent the first several cleavages with normal timing and symmetry, but underwent aberrant cleavages and produced supernumerary large blastomeres during the time that the control embryos generated teloblasts. Once the teloblasts were formed, the microinjection of alpha-amanitin did not affect the production of blast cells by the teloblasts, but it did block the divisions and movements of the blast cells and the micromere-derived cells. These data suggest that zygotic transcription is activated during the early cleavages of Helobdella embryos and that newly synthesized transcripts are required for the generation of teloblasts. Thus, there is an early, critical period of messenger RNA synthesis essential for teloblast production that is distinct from the later phase of messenger RNA synthesis required for cell divisions and cell movements during gastrulation." @default.
• W2091325241 created "2016-06-24" @default.
• W2091325241 creator A5057616646 @default.
• W2091325241 creator A5083850738 @default.
• W2091325241 date "1991-07-01" @default.
• W2091325241 modified "2023-10-15" @default.
• W2091325241 title "Transcription in leech: mRNA synthesis is required for early cleavages in Helobdella embryos" @default.
• W2091325241 cites W1574903825 @default.
• W2091325241 cites W1595657183 @default.
• W2091325241 cites W1597363112 @default.
• W2091325241 cites W1781095925 @default.
• W2091325241 cites W1834644249 @default.
• W2091325241 cites W1966550437 @default.
• W2091325241 cites W1967041590 @default.
• W2091325241 cites W1971657040 @default.
• W2091325241 cites W1978905180 @default.
• W2091325241 cites W1983814468 @default.
• W2091325241 cites W1987654848 @default.
• W2091325241 cites W1992660341 @default.
• W2091325241 cites W1992982553 @default.
• W2091325241 cites W1994758233 @default.
• W2091325241 cites W1995004462 @default.
• W2091325241 cites W1995338652 @default.
• W2091325241 cites W1998616017 @default.
• W2091325241 cites W2000789135 @default.
• W2091325241 cites W2000880684 @default.
• W2091325241 cites W2003286607 @default.
• W2091325241 cites W2005906206 @default.
• W2091325241 cites W2014993354 @default.
• W2091325241 cites W2021559164 @default.
• W2091325241 cites W2028365248 @default.
• W2091325241 cites W2033293260 @default.
• W2091325241 cites W2051213538 @default.
• W2091325241 cites W2051719835 @default.
• W2091325241 cites W2064428517 @default.
• W2091325241 cites W2067913743 @default.
• W2091325241 cites W2070347944 @default.
• W2091325241 cites W2077500199 @default.
• W2091325241 cites W2086896040 @default.
• W2091325241 cites W2087433592 @default.
• W2091325241 cites W2089827318 @default.
• W2091325241 cites W2103431676 @default.
• W2091325241 cites W2107332774 @default.
• W2091325241 cites W2131518991 @default.
• W2091325241 cites W2137539263 @default.
• W2091325241 cites W2151687078 @default.
• W2091325241 cites W2163350560 @default.
• W2091325241 cites W2346128454 @default.
• W2091325241 cites W2416080818 @default.
• W2091325241 doi "https://doi.org/10.1016/0012-1606(91)90442-6" @default.
• W2091325241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2060698" @default.
• W2091325241 hasPublicationYear "1991" @default.
• W2091325241 type Work @default.
• W2091325241 sameAs 2091325241 @default.
• W2091325241 citedByCount "31" @default.
• W2091325241 countsByYear W20913252412013 @default.
• W2091325241 countsByYear W20913252412017 @default.
• W2091325241 crossrefType "journal-article" @default.
• W2091325241 hasAuthorship W2091325241A5057616646 @default.
• W2091325241 hasAuthorship W2091325241A5083850738 @default.
• W2091325241 hasConcept C104317684 @default.
• W2091325241 hasConcept C105580179 @default.
• W2091325241 hasConcept C129536746 @default.
• W2091325241 hasConcept C138885662 @default.
• W2091325241 hasConcept C153911025 @default.
• W2091325241 hasConcept C179926584 @default.
• W2091325241 hasConcept C196843134 @default.
• W2091325241 hasConcept C2777804106 @default.
• W2091325241 hasConcept C28748434 @default.
• W2091325241 hasConcept C41895202 @default.
• W2091325241 hasConcept C54355233 @default.
• W2091325241 hasConcept C67705224 @default.
• W2091325241 hasConcept C68760520 @default.
• W2091325241 hasConcept C86803240 @default.
• W2091325241 hasConcept C87073359 @default.
• W2091325241 hasConcept C95444343 @default.
• W2091325241 hasConceptScore W2091325241C104317684 @default.
• W2091325241 hasConceptScore W2091325241C105580179 @default.
• W2091325241 hasConceptScore W2091325241C129536746 @default.
• W2091325241 hasConceptScore W2091325241C138885662 @default.
• W2091325241 hasConceptScore W2091325241C153911025 @default.
• W2091325241 hasConceptScore W2091325241C179926584 @default.
• W2091325241 hasConceptScore W2091325241C196843134 @default.
• W2091325241 hasConceptScore W2091325241C2777804106 @default.
• W2091325241 hasConceptScore W2091325241C28748434 @default.
• W2091325241 hasConceptScore W2091325241C41895202 @default.
• W2091325241 hasConceptScore W2091325241C54355233 @default.
• W2091325241 hasConceptScore W2091325241C67705224 @default.
• W2091325241 hasConceptScore W2091325241C68760520 @default.
• W2091325241 hasConceptScore W2091325241C86803240 @default.
• W2091325241 hasConceptScore W2091325241C87073359 @default.
• W2091325241 hasConceptScore W2091325241C95444343 @default.
• W2091325241 hasIssue "1" @default.
• W2091325241 hasLocation W20913252411 @default.
• W2091325241 hasLocation W20913252412 @default.
• W2091325241 hasOpenAccess W2091325241 @default.
• W2091325241 hasPrimaryLocation W20913252411 @default.
• W2091325241 hasRelatedWork W1536401845 @default.

• next