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- W2091330594 abstract "Adult female rats, hamsters and rabbits were bred and after implantation a copper ring was transfixed through the uterine lumen near the uterotubal junction. The copper ring was left throughout pregnancy and the lactation period. The possible teratological effects of copper were examined. Gestation, parturition and lactation were not affected by the copper. There were no macroscopic anatomical deformities noted in F1 and F2 generations. The fertility of F1 and F2 generations was normal. There were no significant differences in body weights and organ weights between offspring of copper treated and untreated mothers in either sex of the F1 and F2 generations. Histological examination of the ovaries, uteri and adrenals of Parent females showed no deviation from normal. The female and male reproductive tissues of F1 and F2 generations did not show abnormalities histologically. It can be concluded from this study that according to the conditions of these experiments, copper wire does not influence reproductive function and produces no teratological effects in rats, hamsters and rabbits." @default.
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- W2091330594 date "1973-05-01" @default.
- W2091330594 modified "2023-09-24" @default.
- W2091330594 title "Absence of teratogenicity of intrauterine copper wire in rats, hamsters and rabbits" @default.
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- W2091330594 doi "https://doi.org/10.1016/0010-7824(73)90142-x" @default.
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