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• W2091472299 abstract "In this work, a novel fluorescence biosensor was demonstrated for detection of Hg2+ ions with relatively high selectivity and sensitivity. The sensing scheme was based on G-quenching induced by Hg2+ ions. In the presence of Hg2+ ions, the single-stranded signal probe which has carboxylfluorescein (FAM) and guanine segment at its 5′ and 3′ ends, respectively, folded into duplex-like structure via the Hg2+-mediated coordination of T–Hg2+–T base pairs. It brought guannine segment close to the dye and caused a remarkable decrease of fluorescence signal. The sensor showed a sensitive response to Hg2+ ions in a concentration range from 0.5 to 10 μM, and a detection limit of 0.5 nM was given. This homogeneous system required only a single-labeled oligonucleotide, operated by concise procedures, and possessed comparable sensitivity as previous approaches. Furthermore, the sensor exhibits a great perspective for future practical applications." @default.
• W2091472299 created "2016-06-24" @default.
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• W2091472299 date "2011-07-01" @default.
• W2091472299 modified "2023-10-16" @default.
• W2091472299 title "A simple and sensitive fluorescent sensing platform for Hg2+ ions assay based on G-quenching" @default.
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• W2091472299 doi "https://doi.org/10.1016/j.talanta.2011.04.063" @default.
• W2091472299 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21645763" @default.
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