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- W2091541631 abstract "To assess the influence of autonomic neuropathy on toe blood pressure (TBP), a parameter used currently as an ischemic index.The age-matched study subjects included 20 non-insulin-dependent diabetes mellitus (NIDDM) patients with autonomic neuropathy (DN) and 10 NIDDM patients without autonomic neuropathy (D), assessed by standard cardiovascular tests and galvanic skin response, and 8 control subjects (C). None of the subjects had peripheral vascular disease (PVD) (ankle/brachial index 0.9-1.1.The TBP and toe/brachial index (TBI) were significantly lower in DN than in C and D (P < 0.01). The saturation index (SI), the ratio between foot venous and arterial partial pressure of oxygen (PO2), was significantly higher in DN than in C and D (P < 0.05). An inverse relationship was found between TBI and SI (r = 0.554, P = 0.001).The autonomic nervous system directly influences peripheral circulation. In diabetic patients without PVD, a failure of sympathetic fibers caused by autonomic neuropathy could lead to a reduction of TBP. Therefore, TBP cannot be used as an ischemic index in diabetic patients." @default.
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- W2091541631 date "1994-04-01" @default.
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- W2091541631 title "Autonomic Neuropathy Influences Great Toe Blood Pressure" @default.
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- W2091541631 doi "https://doi.org/10.2337/diacare.17.4.284" @default.
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