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- W2091553655 abstract "Three techniques for the preparation of leukocyte poor red blood cell concentrates are described. The final step of each technique amploys microaggregate blood filtration to remove large quantities of aggregated white cells from the blood. The first technique, microaggregated blood filtration alone, removes 67% of the leukocytes from stored blood. The second procedure, high speed centrifugation followed by microaggregate filtration, eliminates 83% of the WBC. The final technique, centrifugation followed by 3 hours of refrigeration and filtration, removes >85% of the leukocytes from fresh blood. The efficiency of each technique varies directly with the unit's storage age. The red cell loss imposed by these procedures averages >8%. Transfusion of the products produced by these procedures was shown to reduce the likelihood of febrile transfusion reactions by as much as 40-fold. The techniques offer several advantages over those procedures, currently used to produce leukocyte poor blood, viz. cost effectiveness, “closed system processing”, ready availability, and red cell conservation." @default.
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- W2091553655 date "1984-01-01" @default.
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- W2091553655 title "Semiquantitative purification of red cell concentrates by aggregation and selective filtration." @default.
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- W2091553655 doi "https://doi.org/10.3925/jjtc1958.30.239" @default.
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