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• W2091556263 abstract "Two analogs of the peptide mimicking the 1977-1991 C- terminal part of fibronectin have been synthesized and tested. AWLI simulated human fibronectin fragment 1977-1991, whereas AWLII hybridized to both RGD and 1977-1991 fragments. AWLI and AWLII peptides inhibited the migration of the ovarian carcinoma cell line OVP10 regardless of the presence RGD. AWLI peptide inhibited spontaneous and fibronectin-activated cell migration and ERK1/2 activity. Neither AWLI nor fibronectin induced changes in FAK proteins, as could be judged from Western blots. In conclusion, it seems that the C-terminal fragment of fibronectin inhibits ERK1/2-dependent (random) migration of ovarian carcinoma cells." @default.
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• W2091556263 date "2001-12-01" @default.
• W2091556263 modified "2023-10-03" @default.
• W2091556263 title "Peptide analog of fibronectin that inhibits cell migration and ERK 1/2 activity" @default.
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• W2091556263 doi "https://doi.org/10.1016/s0196-9781(01)00547-2" @default.
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