FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091571738> ?p ?o ?g. }

• W2091571738 endingPage "S30" @default.
• W2091571738 startingPage "S30" @default.
• W2091571738 abstract "OBJECTIVE: To compare laboratory and clinical outcomes of SIN vs SEQ using sibling oocytes/embryos from day of retrieval to day 6. Also, to better determine the impact of these two types of culture media systems on pregnancy rates (PR), comparisons were made between groups of patients where all oocytes/embryos were placed in either SIN or SEQ. DESIGN: Retrospective study. MATERIALS AND METHODS: All IVF/ICSI patients from June 2007 to January 2008 were analyzed in this study. Patients were separated into one of three groups: a) sibling oocytes split between SIN or SEQ (N=27), b) all oocytes in SEQ (N=43), c) all oocytes in SIN (N=43). SEQ used was from SAGE and it consisted of Fertilization media (day 0-1), Cleavage media (day 1- 3) and Blastocyst media (day 3-6). SIN was Global and eggs/embryos were transferred to fresh drops of media on days 0, 1, 3 and 5. All media was supplemented with 10% Synthetic Protein Substitute and was overlaid with oil. Incubators had an atmosphere of 6.5% CO2 in room air. RESULTS: There were no significant differences in stimulation protocol, age, baseline serum FSH levels or number of embryos transferred between groups. Comparison of sibling embryo delopment demonstrated a significant increase in the number of embryos with > 6 cells on day 3, total blastocyst formation and blastocysts cryopreserved by day 6 in SIN over SEQ. This improved embryo development was also demonstrated when the sibling embryo data was combined with the embryo data from the cases where all the eggs were placed in SEQ or SIN. This also allowed for a comparison of PR. For this comparison, split cases where all the embryos transferred were from only SEQ or SIN were included. However, there were no significant differences in neither clinical nor ongoing pregnancy rates between the cases in SEQ vs SIN.Table 1Sibling oocytesMediaEmbryos with > 6 cells (day 3)Blastocyst FormationBlastocysts CryopreservedSequential43% (103/195)51% (98/190)16% (24/122)Single61% (113/184)∗p <0.001; Chi square.71% (127/178)∗p <0.001; Chi square.26% (32/123)∗ p <0.001; Chi square. Open table in a new tab Table 2All casesMediaEmbryos with > 6 cells (day 3)Blastocyst Formation (day 5-6)Clinical PRSequential43% (257/583)43% (231/537)63% (29/46)Single61% (341/562)∗p<0.001; Chi square.71% (337/505)∗p<0.001; Chi square.69% (36/52)∗ p<0.001; Chi square. Open table in a new tab CONCLUSIONS: These data demonstrate that maintaining eggs/embryos in the same media formulation from the day of egg retrieval to day 6 results in improved embryo development and comparable pregnancy rates when compared to a sequential media system." @default.
• W2091571738 created "2016-06-24" @default.
• W2091571738 creator A5022731640 @default.
• W2091571738 creator A5070504129 @default.
• W2091571738 date "2008-09-01" @default.
• W2091571738 modified "2023-10-16" @default.
• W2091571738 title "Improved embryo development using a single medium (SIN) vs a sequential media (SEQ) system from the day of egg retrieval to day 6: comparison of sibling oocytes" @default.
• W2091571738 doi "https://doi.org/10.1016/j.fertnstert.2008.07.465" @default.
• W2091571738 hasPublicationYear "2008" @default.
• W2091571738 type Work @default.
• W2091571738 sameAs 2091571738 @default.
• W2091571738 citedByCount "1" @default.
• W2091571738 countsByYear W20915717382016 @default.
• W2091571738 crossrefType "journal-article" @default.
• W2091571738 hasAuthorship W2091571738A5022731640 @default.
• W2091571738 hasAuthorship W2091571738A5070504129 @default.
• W2091571738 hasBestOaLocation W20915717381 @default.
• W2091571738 hasConcept C105702510 @default.
• W2091571738 hasConcept C138496976 @default.
• W2091571738 hasConcept C15744967 @default.
• W2091571738 hasConcept C16685009 @default.
• W2091571738 hasConcept C196843134 @default.
• W2091571738 hasConcept C2776194465 @default.
• W2091571738 hasConcept C2778177303 @default.
• W2091571738 hasConcept C2779335785 @default.
• W2091571738 hasConcept C29456083 @default.
• W2091571738 hasConcept C54355233 @default.
• W2091571738 hasConcept C71924100 @default.
• W2091571738 hasConcept C86803240 @default.
• W2091571738 hasConcept C87073359 @default.
• W2091571738 hasConcept C88972607 @default.
• W2091571738 hasConceptScore W2091571738C105702510 @default.
• W2091571738 hasConceptScore W2091571738C138496976 @default.
• W2091571738 hasConceptScore W2091571738C15744967 @default.
• W2091571738 hasConceptScore W2091571738C16685009 @default.
• W2091571738 hasConceptScore W2091571738C196843134 @default.
• W2091571738 hasConceptScore W2091571738C2776194465 @default.
• W2091571738 hasConceptScore W2091571738C2778177303 @default.
• W2091571738 hasConceptScore W2091571738C2779335785 @default.
• W2091571738 hasConceptScore W2091571738C29456083 @default.
• W2091571738 hasConceptScore W2091571738C54355233 @default.
• W2091571738 hasConceptScore W2091571738C71924100 @default.
• W2091571738 hasConceptScore W2091571738C86803240 @default.
• W2091571738 hasConceptScore W2091571738C87073359 @default.
• W2091571738 hasConceptScore W2091571738C88972607 @default.
• W2091571738 hasLocation W20915717381 @default.
• W2091571738 hasOpenAccess W2091571738 @default.
• W2091571738 hasPrimaryLocation W20915717381 @default.
• W2091571738 hasRelatedWork W1983333251 @default.
• W2091571738 hasRelatedWork W2015301454 @default.
• W2091571738 hasRelatedWork W2141284822 @default.
• W2091571738 hasRelatedWork W2166971475 @default.
• W2091571738 hasRelatedWork W2349296746 @default.
• W2091571738 hasRelatedWork W2389182588 @default.
• W2091571738 hasRelatedWork W5535762 @default.
• W2091571738 hasRelatedWork W66626673 @default.
• W2091571738 hasRelatedWork W1974174137 @default.
• W2091571738 hasRelatedWork W2787081964 @default.
• W2091571738 hasVolume "90" @default.
• W2091571738 isParatext "false" @default.
• W2091571738 isRetracted "false" @default.
• W2091571738 magId "2091571738" @default.
• W2091571738 workType "article" @default.