FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091631738> ?p ?o ?g. }

• W2091631738 endingPage "R215" @default.
• W2091631738 startingPage "R215" @default.
• W2091631738 abstract "As data from Clostridium difficile infection (CDI) in intensive care unit (ICU) are still scarce, our objectives were to assess the morbidity and mortality of ICU-acquired CDI. We compared patients with ICU-acquired CDI (watery or unformed stools occurring ≥ 72 hours after ICU admission with a stool sample positive for C. difficile toxin A or B) with two groups of controls hospitalized at the same time in the same unit. The first control group comprised patients with ICU-acquired diarrhea occurring ≥ 72 hours after ICU admission with a stool sample negative for C. difficile and for toxin A or B. The second group comprised patients without any diarrhea. Among 5,260 patients, 512 patients developed one episode of diarrhea. Among them, 69 (13.5%) had a CDI; 10 (14.5%) of them were community-acquired, contrasting with 12 (17.4%) that were hospital-acquired and 47 (68%) that were ICU-acquired. A pseudomembranous colitis was associated in 24/47 (51%) ICU patients. The median delay between diagnosis and metronidazole administration was one day (25th Quartile; 75th Quartile (0; 2) days). The case-fatality rate for patients with ICU-acquired CDI was 10/47 (21.5%), as compared to 112/443 (25.3%) for patients with negative tests. Neither the crude mortality (cause specific hazard ratio; CSHR = 0.70, 95% confidence interval; CI 0.36 to 1.35, P = 0.3) nor the adjusted mortality to confounding variables (CSHR = 0.81, 95% CI 0.4 to 1.64, P = 0.6) were significantly different between CDI patients and diarrheic patients without CDI. Compared to the general ICU population, neither the crude mortality (SHR = 0.64, 95% CI 0.34 to 1.21, P = 0.17), nor the mortality adjusted to confounding variables (CSHR = 0.71, 95% confidence interval (CI) 0.38 to 1.35, P = 0.3), were significantly different between the two groups. The estimated increase in the duration of stay due to CDI was 8.0 days ± 9.3 days, (P = 0.4) in comparison to the diarrheic population, and 6.3 days ± 4.3 (P = 0.14) in comparison to the general ICU population. If treated early, ICU-acquired CDI is not independently associated with an increased mortality and impacts marginally the ICU length of stay." @default.
• W2091631738 created "2016-06-24" @default.
• W2091631738 creator A5009747210 @default.
• W2091631738 creator A5012692234 @default.
• W2091631738 creator A5033121336 @default.
• W2091631738 creator A5039039922 @default.
• W2091631738 creator A5039514260 @default.
• W2091631738 creator A5044713281 @default.
• W2091631738 creator A5057372078 @default.
• W2091631738 creator A5060480896 @default.
• W2091631738 creator A5061387679 @default.
• W2091631738 creator A5075715397 @default.
• W2091631738 creator A5082680741 @default.
• W2091631738 date "2012-01-01" @default.
• W2091631738 modified "2023-10-17" @default.
• W2091631738 title "Outcome of ICU patients with Clostridium difficile infection" @default.
• W2091631738 cites W1898928487 @default.
• W2091631738 cites W1949517763 @default.
• W2091631738 cites W1986154343 @default.
• W2091631738 cites W2003614970 @default.
• W2091631738 cites W2014136077 @default.
• W2091631738 cites W2015364705 @default.
• W2091631738 cites W2026016516 @default.
• W2091631738 cites W2040684206 @default.
• W2091631738 cites W2041613596 @default.
• W2091631738 cites W2043436644 @default.
• W2091631738 cites W2046549547 @default.
• W2091631738 cites W2056233231 @default.
• W2091631738 cites W2058840909 @default.
• W2091631738 cites W2083363528 @default.
• W2091631738 cites W2100344755 @default.
• W2091631738 cites W2101233913 @default.
• W2091631738 cites W2110111681 @default.
• W2091631738 cites W2112412018 @default.
• W2091631738 cites W2126995265 @default.
• W2091631738 cites W2135720943 @default.
• W2091631738 cites W2154746519 @default.
• W2091631738 cites W2158074760 @default.
• W2091631738 cites W2171894418 @default.
• W2091631738 cites W4247943214 @default.
• W2091631738 doi "https://doi.org/10.1186/cc11852" @default.
• W2091631738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3672590" @default.
• W2091631738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23127327" @default.
• W2091631738 hasPublicationYear "2012" @default.
• W2091631738 type Work @default.
• W2091631738 sameAs 2091631738 @default.
• W2091631738 citedByCount "46" @default.
• W2091631738 countsByYear W20916317382013 @default.
• W2091631738 countsByYear W20916317382014 @default.
• W2091631738 countsByYear W20916317382015 @default.
• W2091631738 countsByYear W20916317382016 @default.
• W2091631738 countsByYear W20916317382017 @default.
• W2091631738 countsByYear W20916317382018 @default.
• W2091631738 countsByYear W20916317382019 @default.
• W2091631738 countsByYear W20916317382020 @default.
• W2091631738 countsByYear W20916317382021 @default.
• W2091631738 countsByYear W20916317382022 @default.
• W2091631738 countsByYear W20916317382023 @default.
• W2091631738 crossrefType "journal-article" @default.
• W2091631738 hasAuthorship W2091631738A5009747210 @default.
• W2091631738 hasAuthorship W2091631738A5012692234 @default.
• W2091631738 hasAuthorship W2091631738A5033121336 @default.
• W2091631738 hasAuthorship W2091631738A5039039922 @default.
• W2091631738 hasAuthorship W2091631738A5039514260 @default.
• W2091631738 hasAuthorship W2091631738A5044713281 @default.
• W2091631738 hasAuthorship W2091631738A5057372078 @default.
• W2091631738 hasAuthorship W2091631738A5060480896 @default.
• W2091631738 hasAuthorship W2091631738A5061387679 @default.
• W2091631738 hasAuthorship W2091631738A5075715397 @default.
• W2091631738 hasAuthorship W2091631738A5082680741 @default.
• W2091631738 hasBestOaLocation W20916317381 @default.
• W2091631738 hasConcept C107130276 @default.
• W2091631738 hasConcept C126322002 @default.
• W2091631738 hasConcept C187316915 @default.
• W2091631738 hasConcept C207103383 @default.
• W2091631738 hasConcept C2776376669 @default.
• W2091631738 hasConcept C2777396551 @default.
• W2091631738 hasConcept C2779802037 @default.
• W2091631738 hasConcept C2991793726 @default.
• W2091631738 hasConcept C2994496256 @default.
• W2091631738 hasConcept C44249647 @default.
• W2091631738 hasConcept C501593827 @default.
• W2091631738 hasConcept C68443243 @default.
• W2091631738 hasConcept C71924100 @default.
• W2091631738 hasConcept C86803240 @default.
• W2091631738 hasConcept C89423630 @default.
• W2091631738 hasConceptScore W2091631738C107130276 @default.
• W2091631738 hasConceptScore W2091631738C126322002 @default.
• W2091631738 hasConceptScore W2091631738C187316915 @default.
• W2091631738 hasConceptScore W2091631738C207103383 @default.
• W2091631738 hasConceptScore W2091631738C2776376669 @default.
• W2091631738 hasConceptScore W2091631738C2777396551 @default.
• W2091631738 hasConceptScore W2091631738C2779802037 @default.
• W2091631738 hasConceptScore W2091631738C2991793726 @default.
• W2091631738 hasConceptScore W2091631738C2994496256 @default.
• W2091631738 hasConceptScore W2091631738C44249647 @default.
• W2091631738 hasConceptScore W2091631738C501593827 @default.
• W2091631738 hasConceptScore W2091631738C68443243 @default.

• next