Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091655838> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2091655838 abstract "Objective: To report blood pressure elevation associated with rofecoxib use in 2 older adults. Case Summaries: Two patients, aged 75 and 94 years, were prescribed rofecoxib for osteoarthritis pain. After the initiation of therapy, an elevation in systolic blood pressure measurement ≥17 mm Hg was observed. Upon withdrawal of rofecoxib, blood pressure in one patient returned to baseline measurements. In the second patient, sustained rofecoxib use resulted in blood pressure elevation and change in antihypertensive therapy. Discussion: It is well known that even a small elevation in blood pressure can significantly increase a person's risk for cardiovascular events. However, little is known about the potential magnitude of blood pressure elevation with the use of cyclooxygenase-2 inhibitors in the older adult population. In 2 older adults with osteoarthritis and hypertension, rofecoxib potentially led to a substantial elevation in blood pressure. In each case, adjustments of respective therapeutic regimens were made. The Naranjo probability scale indicates a probable relationship in both cases between the rofecoxib and blood pressure elevation. Conclusions: These reports suggest that rofecoxib could produce greater elevation in blood pressure in older hypertensive adults than has been previously reported. Therefore, close monitoring of blood pressure for 1–2 months after initiation of rofecoxib therapy is advisable. Further study is needed to determine the true clinical significance of these findings in older hypertensive adults." @default.
- W2091655838 created "2016-06-24" @default.
- W2091655838 creator A5006361518 @default.
- W2091655838 creator A5087749575 @default.
- W2091655838 date "2004-03-01" @default.
- W2091655838 modified "2023-09-26" @default.
- W2091655838 title "Blood Pressure Elevation with Rofecoxib in Older Adults" @default.
- W2091655838 cites W1969239240 @default.
- W2091655838 cites W1975553698 @default.
- W2091655838 cites W1980346717 @default.
- W2091655838 cites W1983033883 @default.
- W2091655838 cites W1983370454 @default.
- W2091655838 cites W1983398430 @default.
- W2091655838 cites W2018035901 @default.
- W2091655838 cites W2040386378 @default.
- W2091655838 cites W2042274378 @default.
- W2091655838 cites W2054825239 @default.
- W2091655838 cites W2062159035 @default.
- W2091655838 cites W2062335942 @default.
- W2091655838 cites W2065689558 @default.
- W2091655838 cites W2067339994 @default.
- W2091655838 cites W2067978628 @default.
- W2091655838 cites W2082499830 @default.
- W2091655838 cites W2107864895 @default.
- W2091655838 cites W2146625461 @default.
- W2091655838 cites W2147254207 @default.
- W2091655838 cites W2292074017 @default.
- W2091655838 cites W3022929210 @default.
- W2091655838 doi "https://doi.org/10.1177/875512250402000204" @default.
- W2091655838 hasPublicationYear "2004" @default.
- W2091655838 type Work @default.
- W2091655838 sameAs 2091655838 @default.
- W2091655838 citedByCount "0" @default.
- W2091655838 crossrefType "journal-article" @default.
- W2091655838 hasAuthorship W2091655838A5006361518 @default.
- W2091655838 hasAuthorship W2091655838A5087749575 @default.
- W2091655838 hasConcept C126322002 @default.
- W2091655838 hasConcept C164705383 @default.
- W2091655838 hasConcept C181199279 @default.
- W2091655838 hasConcept C185592680 @default.
- W2091655838 hasConcept C2778582115 @default.
- W2091655838 hasConcept C2779689624 @default.
- W2091655838 hasConcept C55493867 @default.
- W2091655838 hasConcept C71924100 @default.
- W2091655838 hasConcept C84393581 @default.
- W2091655838 hasConceptScore W2091655838C126322002 @default.
- W2091655838 hasConceptScore W2091655838C164705383 @default.
- W2091655838 hasConceptScore W2091655838C181199279 @default.
- W2091655838 hasConceptScore W2091655838C185592680 @default.
- W2091655838 hasConceptScore W2091655838C2778582115 @default.
- W2091655838 hasConceptScore W2091655838C2779689624 @default.
- W2091655838 hasConceptScore W2091655838C55493867 @default.
- W2091655838 hasConceptScore W2091655838C71924100 @default.
- W2091655838 hasConceptScore W2091655838C84393581 @default.
- W2091655838 hasLocation W20916558381 @default.
- W2091655838 hasOpenAccess W2091655838 @default.
- W2091655838 hasPrimaryLocation W20916558381 @default.
- W2091655838 hasRelatedWork W1844224389 @default.
- W2091655838 hasRelatedWork W1990967593 @default.
- W2091655838 hasRelatedWork W2006471244 @default.
- W2091655838 hasRelatedWork W2053923652 @default.
- W2091655838 hasRelatedWork W2070193668 @default.
- W2091655838 hasRelatedWork W2236334655 @default.
- W2091655838 hasRelatedWork W2418138138 @default.
- W2091655838 hasRelatedWork W2563157208 @default.
- W2091655838 hasRelatedWork W2765804565 @default.
- W2091655838 hasRelatedWork W2771418204 @default.
- W2091655838 hasRelatedWork W2899489863 @default.
- W2091655838 hasRelatedWork W2926551116 @default.
- W2091655838 hasRelatedWork W2975714771 @default.
- W2091655838 hasRelatedWork W3021951354 @default.
- W2091655838 hasRelatedWork W3122050617 @default.
- W2091655838 hasRelatedWork W3155227059 @default.
- W2091655838 hasRelatedWork W3197969718 @default.
- W2091655838 hasRelatedWork W3200152181 @default.
- W2091655838 hasRelatedWork W773691545 @default.
- W2091655838 hasRelatedWork W2556977412 @default.
- W2091655838 isParatext "false" @default.
- W2091655838 isRetracted "false" @default.
- W2091655838 magId "2091655838" @default.
- W2091655838 workType "article" @default.