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- W2091665334 abstract "A desmutagenic factor was isolated from burdock (Arctium lappa Linne). This factor reduced the mutagenicity of mutagens that are active without metabolic activation, such as 4-NO2-1,2-DAB and 2-NO2-1,4-DAB, as well as mutagens such as ethidium bromide, 2-aminoanthracene, Trp-P-1 and Trp-P-2 requiring S9 for metabolic activation. It is resistant to heat and proteolytic enzymes and sensitive to treatment with MnCl2. The partially purified principles had a molecular weight higher than 300 000 and showed characteristics of a polyanionic substance. An irreversible diminution of the mutagen was confirmed by treatment of 2-NO2-1,4-DAB or Trp-P-2 with the burdock factor." @default.
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- W2091665334 date "1984-10-01" @default.
- W2091665334 modified "2023-09-28" @default.
- W2091665334 title "A desmutagenic factor isolated from burdock (Arctium lappa Linne)" @default.
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- W2091665334 doi "https://doi.org/10.1016/0027-5107(84)90119-2" @default.
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