Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091665357> ?p ?o ?g. }
- W2091665357 endingPage "688" @default.
- W2091665357 startingPage "683" @default.
- W2091665357 abstract "Elongation factor Tu (EF-Tu), the most abundant protein in Escherichia coli, is a guanine nucleotide-binding protein that in the ‘on’ state acts as a carrier of amino acyl-tRNA to the ribosome. Our knowledge of this essential component of translation has brought substantial progress in the past decade thanks to the co-ordinated application of biochemical, physico-chemical and genetic methods. Crystallographic analysis at 2.6 Å resolution and site-directed mutagenesis have revealed structural and functional similarities between the guanine nucleotide-binding domains of EF-Tu and human H-ras p21 protein. The regulation of the expression of the two EF-Tu-encoding genes in E. coli, particularly that of tufB, has been shown to involve diverse mechanisms. Several aspects of the functions of EF-Tu in the elongation cycle have been reinvestigated, leading to new insights. These studies have emphasized the manifold aspects of the mechanisms regulating the activity of EF-Tu in the bacterial cell." @default.
- W2091665357 created "2016-06-24" @default.
- W2091665357 creator A5004713612 @default.
- W2091665357 creator A5013337662 @default.
- W2091665357 creator A5014919267 @default.
- W2091665357 creator A5024933867 @default.
- W2091665357 creator A5063128052 @default.
- W2091665357 date "1992-03-01" @default.
- W2091665357 modified "2023-10-13" @default.
- W2091665357 title "Elongation factor Tu: a molecular switch in protein biosynthesis" @default.
- W2091665357 cites W1550254361 @default.
- W2091665357 cites W1573346879 @default.
- W2091665357 cites W1586275583 @default.
- W2091665357 cites W1591464913 @default.
- W2091665357 cites W1597352920 @default.
- W2091665357 cites W1799697816 @default.
- W2091665357 cites W1830841014 @default.
- W2091665357 cites W1851336625 @default.
- W2091665357 cites W1962687575 @default.
- W2091665357 cites W1973694785 @default.
- W2091665357 cites W1975530267 @default.
- W2091665357 cites W1977598234 @default.
- W2091665357 cites W1980067542 @default.
- W2091665357 cites W2001690457 @default.
- W2091665357 cites W2002563246 @default.
- W2091665357 cites W2006622978 @default.
- W2091665357 cites W2010625691 @default.
- W2091665357 cites W2012069281 @default.
- W2091665357 cites W2012975635 @default.
- W2091665357 cites W2018898595 @default.
- W2091665357 cites W2020305960 @default.
- W2091665357 cites W2020341797 @default.
- W2091665357 cites W2023280070 @default.
- W2091665357 cites W2025444341 @default.
- W2091665357 cites W2028011256 @default.
- W2091665357 cites W2029776092 @default.
- W2091665357 cites W2037339623 @default.
- W2091665357 cites W2039540684 @default.
- W2091665357 cites W2043783701 @default.
- W2091665357 cites W2047314239 @default.
- W2091665357 cites W2056626638 @default.
- W2091665357 cites W2059822616 @default.
- W2091665357 cites W2064102520 @default.
- W2091665357 cites W2067711179 @default.
- W2091665357 cites W2071078908 @default.
- W2091665357 cites W2074129396 @default.
- W2091665357 cites W2074616759 @default.
- W2091665357 cites W2077101972 @default.
- W2091665357 cites W2091077037 @default.
- W2091665357 cites W2095128393 @default.
- W2091665357 cites W2105352059 @default.
- W2091665357 cites W2114767715 @default.
- W2091665357 cites W2115960920 @default.
- W2091665357 cites W2119965520 @default.
- W2091665357 cites W2155338846 @default.
- W2091665357 cites W2155373804 @default.
- W2091665357 cites W2292991807 @default.
- W2091665357 cites W2295712116 @default.
- W2091665357 cites W32286231 @default.
- W2091665357 cites W97812311 @default.
- W2091665357 doi "https://doi.org/10.1111/j.1365-2958.1992.tb01516.x" @default.
- W2091665357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1573997" @default.
- W2091665357 hasPublicationYear "1992" @default.
- W2091665357 type Work @default.
- W2091665357 sameAs 2091665357 @default.
- W2091665357 citedByCount "73" @default.
- W2091665357 countsByYear W20916653572012 @default.
- W2091665357 countsByYear W20916653572013 @default.
- W2091665357 countsByYear W20916653572014 @default.
- W2091665357 countsByYear W20916653572015 @default.
- W2091665357 countsByYear W20916653572017 @default.
- W2091665357 countsByYear W20916653572018 @default.
- W2091665357 countsByYear W20916653572019 @default.
- W2091665357 countsByYear W20916653572020 @default.
- W2091665357 countsByYear W20916653572021 @default.
- W2091665357 countsByYear W20916653572022 @default.
- W2091665357 countsByYear W20916653572023 @default.
- W2091665357 crossrefType "journal-article" @default.
- W2091665357 hasAuthorship W2091665357A5004713612 @default.
- W2091665357 hasAuthorship W2091665357A5013337662 @default.
- W2091665357 hasAuthorship W2091665357A5014919267 @default.
- W2091665357 hasAuthorship W2091665357A5024933867 @default.
- W2091665357 hasAuthorship W2091665357A5063128052 @default.
- W2091665357 hasBestOaLocation W20916653571 @default.
- W2091665357 hasConcept C104317684 @default.
- W2091665357 hasConcept C105580179 @default.
- W2091665357 hasConcept C126619667 @default.
- W2091665357 hasConcept C139124968 @default.
- W2091665357 hasConcept C149364088 @default.
- W2091665357 hasConcept C153957851 @default.
- W2091665357 hasConcept C16318435 @default.
- W2091665357 hasConcept C207332259 @default.
- W2091665357 hasConcept C2778301229 @default.
- W2091665357 hasConcept C3675279 @default.
- W2091665357 hasConcept C501734568 @default.
- W2091665357 hasConcept C512185932 @default.
- W2091665357 hasConcept C54355233 @default.
- W2091665357 hasConcept C547475151 @default.