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- W2091679077 abstract "Telomeres are protective caps for chromosome ends that are essential for genome stability. Broken chromosomes missing a telomere will not be maintained unless the chromosome is ‘healed’ with the formation of a new telomere. Chromosome healing can be a programmed event following developmentally regulated chromosome fragmentation, or it may occur spontaneously when a chromosome is accidentally broken. In this article we discuss the consequences of telomere loss and the possible mechanisms that the enzyme telomerase employs to form telomeres de novo on broken chromosome ends." @default.
- W2091679077 created "2016-06-24" @default.
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- W2091679077 date "1996-04-01" @default.
- W2091679077 modified "2023-10-18" @default.
- W2091679077 title "Chromosome healing: Spontaneous and programmedde novo telomere formation by telomerase" @default.
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- W2091679077 doi "https://doi.org/10.1002/bies.950180408" @default.
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