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- W2091717766 abstract "Electrolyte-gate amorphous silicon thin-film transistors (EG-TFT) are used for pH and label-free sensing of biological molecules. In top-gate EG-TFTs, the metal gate is replaced by an electrolyte solution, in which a biasing Pt electrode is immersed. It is possible to switch the TFT on by increasing the voltage of the Pt electrode above a threshold value (VT). EG-TFTs show a decrease in VT when the pH of the electrolyte solution is increased. EG-TFTs also show a shift in VT when exposed to solutions containing molecules of either DNA (VT decreases) or the protein horseradish peroxidase (HRP) (VT increases). Exposure to these solutions results in the adsorption of biomolecules at the dielectric-electrolyte interface which changes the TFT transfer curve and consequently allows electronic label-free detection of the biomolecules." @default.
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- W2091717766 date "2006-06-01" @default.
- W2091717766 modified "2023-10-11" @default.
- W2091717766 title "Label-free electronic detection of biomolecules using a-Si:H field-effect devices" @default.
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- W2091717766 doi "https://doi.org/10.1016/j.jnoncrysol.2006.01.058" @default.
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