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- W2091731271 abstract "The specific beta-amyloid(25-35) fragment induced cellular degradation of the human neuroblastoma cell line SH-SY5Y, but did not elicit an effect on the levels of interleukin-1beta and interleukin-1beta converting enzyme, as determined by semiquantitative reverse transcription-polymerase chain reaction and immunocytochemical analysis. The assays revealed constitutive expression of these proteins both at mRNA and protein level. It is conceivable that in the absence of glial elements, such as in the present neuroblastoma cell line, beta-amyloid triggers the toxicity through a direct action and/or through the production of other harmful molecules." @default.
- W2091731271 created "2016-06-24" @default.
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- W2091731271 date "2000-03-09" @default.
- W2091731271 modified "2023-10-01" @default.
- W2091731271 title "IL-1β and ICE mRNA are not altered upon β-amyloid25–35 induced neurotoxicity in human neuroblastoma cells" @default.
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- W2091731271 doi "https://doi.org/10.1016/s0736-5748(99)00092-1" @default.
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