FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091749903> ?p ?o ?g. }

• W2091749903 endingPage "231" @default.
• W2091749903 startingPage "222" @default.
• W2091749903 abstract "Background: This study examines: 1) alveolar bone loss (ABL), a hallmark of periodontitis, in anti‐citrullinated protein antibody (ACPA)‐positive rheumatoid arthritis (RA) patients versus control patients with osteoarthritis (OA); and 2) the association of ABL with RA disease activity and ACPA concentrations, including multiple antigen–specific ACPA. Methods: This multicenter case‐control study includes 617 patients diagnosed with RA (n = 287) or OA (n = 330). Panoramic radiographs were taken; patients were categorized into low, moderate, or high tertiles based on mean percentage ABL. Serum ACPA was measured using second‐generation anticyclic citrullinated peptide enzyme‐linked immunosorbent assay and a multiplex platform to assess distinct antigen‐specific ACPA. A generalized linear mixed model for binary data was used to compare stratified ABL in RA versus OA patients. Associations of moderate and high ABL (versus low) with RA disease activity and severity measures were examined using multivariate regression. Antigen‐specific ACPA responses were compared among ABL tertiles using significance analysis of microarrays. Results: ACPA‐positive patients with RA had a significantly higher mean percentage of sites with ABL >20% compared with patients with OA ( P = 0.03). After multivariate adjustment, greater ABL was significantly associated with higher serum ACPA concentration ( P = 0.004), 28‐joint Disease Activity Score ( P = 0.023), health assessment questionnaire disability ( P = 0.05), tender joint count ( P = 0.02) and joint space narrowing scores ( P = 0.05) among patients with RA. ACPAs targeting citrullinated vimentin and histone were significantly higher in moderate and high ABL groups versus low, regardless of smoking status ( q <0.1%). Conclusions: Greater ABL was associated with higher ACPA, consistent with findings at articular sites. ACPA targeting could provide novel insight into important linkages between RA and periodontitis." @default.
• W2091749903 created "2016-06-24" @default.
• W2091749903 creator A5008207671 @default.
• W2091749903 creator A5014721829 @default.
• W2091749903 creator A5014846160 @default.
• W2091749903 creator A5037707081 @default.
• W2091749903 creator A5037863060 @default.
• W2091749903 creator A5038088512 @default.
• W2091749903 creator A5046429545 @default.
• W2091749903 creator A5049420631 @default.
• W2091749903 creator A5050498402 @default.
• W2091749903 creator A5056036583 @default.
• W2091749903 creator A5070468347 @default.
• W2091749903 creator A5086105954 @default.
• W2091749903 creator A5091214306 @default.
• W2091749903 date "2015-02-01" @default.
• W2091749903 modified "2023-10-03" @default.
• W2091749903 title "Alveolar Bone Loss Is Associated With Circulating Anti-Citrullinated Protein Antibody (ACPA) in Patients With Rheumatoid Arthritis" @default.
• W2091749903 cites W1525452891 @default.
• W2091749903 cites W1793781511 @default.
• W2091749903 cites W1943338444 @default.
• W2091749903 cites W1964042179 @default.
• W2091749903 cites W1974718865 @default.
• W2091749903 cites W1987187864 @default.
• W2091749903 cites W1991178845 @default.
• W2091749903 cites W1993094968 @default.
• W2091749903 cites W1997449106 @default.
• W2091749903 cites W2002401357 @default.
• W2091749903 cites W2006560462 @default.
• W2091749903 cites W2012512397 @default.
• W2091749903 cites W2013829757 @default.
• W2091749903 cites W2017290170 @default.
• W2091749903 cites W2025276299 @default.
• W2091749903 cites W2035685260 @default.
• W2091749903 cites W2059251603 @default.
• W2091749903 cites W2065749550 @default.
• W2091749903 cites W2067645583 @default.
• W2091749903 cites W2090483256 @default.
• W2091749903 cites W2096235117 @default.
• W2091749903 cites W2096966555 @default.
• W2091749903 cites W2102096947 @default.
• W2091749903 cites W2105493788 @default.
• W2091749903 cites W2111496861 @default.
• W2091749903 cites W2116840631 @default.
• W2091749903 cites W2118241494 @default.
• W2091749903 cites W2125516576 @default.
• W2091749903 cites W2126525702 @default.
• W2091749903 cites W2138653461 @default.
• W2091749903 cites W2140911657 @default.
• W2091749903 cites W2141521401 @default.
• W2091749903 cites W2141522272 @default.
• W2091749903 cites W2146266354 @default.
• W2091749903 cites W2152348310 @default.
• W2091749903 cites W2156052496 @default.
• W2091749903 cites W2156070134 @default.
• W2091749903 cites W2161098179 @default.
• W2091749903 cites W2171466033 @default.
• W2091749903 cites W2171518994 @default.
• W2091749903 cites W2899434168 @default.
• W2091749903 doi "https://doi.org/10.1902/jop.2014.140425" @default.
• W2091749903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25299390" @default.
• W2091749903 hasPublicationYear "2015" @default.
• W2091749903 type Work @default.
• W2091749903 sameAs 2091749903 @default.
• W2091749903 citedByCount "40" @default.
• W2091749903 countsByYear W20917499032014 @default.
• W2091749903 countsByYear W20917499032015 @default.
• W2091749903 countsByYear W20917499032016 @default.
• W2091749903 countsByYear W20917499032017 @default.
• W2091749903 countsByYear W20917499032018 @default.
• W2091749903 countsByYear W20917499032019 @default.
• W2091749903 countsByYear W20917499032020 @default.
• W2091749903 countsByYear W20917499032021 @default.
• W2091749903 countsByYear W20917499032022 @default.
• W2091749903 countsByYear W20917499032023 @default.
• W2091749903 crossrefType "journal-article" @default.
• W2091749903 hasAuthorship W2091749903A5008207671 @default.
• W2091749903 hasAuthorship W2091749903A5014721829 @default.
• W2091749903 hasAuthorship W2091749903A5014846160 @default.
• W2091749903 hasAuthorship W2091749903A5037707081 @default.
• W2091749903 hasAuthorship W2091749903A5037863060 @default.
• W2091749903 hasAuthorship W2091749903A5038088512 @default.
• W2091749903 hasAuthorship W2091749903A5046429545 @default.
• W2091749903 hasAuthorship W2091749903A5049420631 @default.
• W2091749903 hasAuthorship W2091749903A5050498402 @default.
• W2091749903 hasAuthorship W2091749903A5056036583 @default.
• W2091749903 hasAuthorship W2091749903A5070468347 @default.
• W2091749903 hasAuthorship W2091749903A5086105954 @default.
• W2091749903 hasAuthorship W2091749903A5091214306 @default.
• W2091749903 hasConcept C126322002 @default.
• W2091749903 hasConcept C143998085 @default.
• W2091749903 hasConcept C147483822 @default.
• W2091749903 hasConcept C159654299 @default.
• W2091749903 hasConcept C163764329 @default.
• W2091749903 hasConcept C203014093 @default.
• W2091749903 hasConcept C2777575956 @default.
• W2091749903 hasConcept C71924100 @default.
• W2091749903 hasConcept C90924648 @default.

• next