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- W2091754143 abstract "In 1948, after observing the severe symptoms that followed the ingestion of alcohol in patients taking tetraethylthiuramdisulfide (antabuse®), Jacobsen and Hald, of Denmark, conceived the idea that this drug might be useful in the treatment of chronic alcoholism.1These investigators, associated with Martensen-Larsen and other co-workers,2subsequently reported in some detail the chemistry and pharmacology of tetraethylthiuramdisulfide and their clinical results with 83 patients under treatment with this drug. These studies were received with much interest by the lay and medical press, and, as a result, clinical investigation spread to other countries, such as Sweden, England, Canada, and, finally, the United States. The significant information available has been reviewed by Glud,3Dale and Ebaugh,4and again by Jacobsen and Martensen-Larsen.5Some of the short-term results have been promising, but long-term studies are still being anxiously awaited. It seems timely to temper the current trend of" @default.
- W2091754143 created "2016-06-24" @default.
- W2091754143 creator A5044238038 @default.
- W2091754143 date "1952-06-07" @default.
- W2091754143 modified "2023-10-18" @default.
- W2091754143 title "DEATH FOLLOWING TEST DRINK OF ALCOHOL IN PATIENTS RECEIVING ANTABUSE®" @default.
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- W2091754143 doi "https://doi.org/10.1001/jama.1952.72930230001012" @default.
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