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- W2091761980 abstract "A simple and sensitive high-pressure liquid chromatographic (HPLC) determination of pseudoephedrine and chlorpheniramine in a pharmaceutical dosage form is described. Quantities of 1.5 μg of pseudoephedrine and 0.1 pg of chlorpheniramine are sufficient to determine concentrations in an aqueous solution. Small volume samples, without any extraction procedures, can be treated for direct drug concentration measurement with a high-pressure liquid chromatograph. The stability-indicating property and the accuracy of this method are comparable to those of an established GLC method. The HPLC method can be applied directly and successfully for dissolution studies. The latter application eliminates the need for volume replacement or subsequent mathematical corrections." @default.
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- W2091761980 date "1978-12-01" @default.
- W2091761980 modified "2023-09-25" @default.
- W2091761980 title "Simultaneous Determination of Pseudoephedrine and Chlorpheniramine in Pharmaceutical Dosage Forms" @default.
- W2091761980 cites W1978715002 @default.
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- W2091761980 doi "https://doi.org/10.1002/jps.2600671208" @default.
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