Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091781418> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2091781418 endingPage "134" @default.
- W2091781418 startingPage "127" @default.
- W2091781418 abstract "PCR in combination with SSO probes was used to analyze the polymorphism in exons 2 and 3 of HLA-B27 subtypes and HLA-C-related alleles in two genetically distant Caucasian groups: Spanish and Jewish populations. AS patients and healthy B27 donors from both populations were analyzed in order to ascertain B27-Cw haplotypes. Three different ancestral haplotypes were found to be represented in both populations: B∗2705/Cw∗0102, B∗2705/Cw∗02022, and B∗2702/Cw∗02022. The B∗2705 (92.5%) was the most frequent allele found in the Spanish population, carried by B∗2705/Cw∗0102 (60.9%) and B2705/Cw∗02022 (30.4%) haplotypes. In contrast, B∗2702 (59.4%) was the most prevalent allele found in the Jewish population and was carried by the B∗2702/Cw∗02022 (63.3%) haplotype. No different allelic and haplotypic distributions were among healthy and AS patients in either Spanish or Jewish populations. The differences found in the distribution of B27 haplotypes among Spanish and Jewish Caucasian populations are consistent with the genetic distance of these ethnic groups. When the Jewish population was subdivided into Ashkenazi (A) and non-Ashkenazi (NA) groups, no significant differences were observed in the distribution of B∗2702/Cw∗02022 haplotype. Minor differences were observed in the underrepresented B∗2705 haplotypes. The present results reflect the ancestral affinities of A and NA Jewish populations. A possible HLA-B27 evolutive pathway in Caucasians is proposed according to the data available for the B27/Cw ancestral haplotypes in Spanish and Jewish groups." @default.
- W2091781418 created "2016-06-24" @default.
- W2091781418 creator A5015397357 @default.
- W2091781418 creator A5017625454 @default.
- W2091781418 creator A5025686273 @default.
- W2091781418 creator A5028973316 @default.
- W2091781418 creator A5028997035 @default.
- W2091781418 creator A5032408537 @default.
- W2091781418 creator A5040017671 @default.
- W2091781418 creator A5072654868 @default.
- W2091781418 date "1994-10-01" @default.
- W2091781418 modified "2023-10-17" @default.
- W2091781418 title "Molecular analysis of HLA-B27 haplotypes in caucasoids frequencies of B27-Cw in jewish and spanish populations" @default.
- W2091781418 cites W1974823499 @default.
- W2091781418 cites W1977385060 @default.
- W2091781418 cites W1982431823 @default.
- W2091781418 cites W1997474892 @default.
- W2091781418 cites W2030234281 @default.
- W2091781418 cites W2030835988 @default.
- W2091781418 cites W2032093766 @default.
- W2091781418 cites W2034488407 @default.
- W2091781418 cites W2069066407 @default.
- W2091781418 cites W2078642485 @default.
- W2091781418 cites W2089121667 @default.
- W2091781418 cites W2094312957 @default.
- W2091781418 cites W2102775790 @default.
- W2091781418 cites W2172065603 @default.
- W2091781418 cites W2338072779 @default.
- W2091781418 cites W3140308691 @default.
- W2091781418 doi "https://doi.org/10.1016/0198-8859(94)90005-1" @default.
- W2091781418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7860357" @default.
- W2091781418 hasPublicationYear "1994" @default.
- W2091781418 type Work @default.
- W2091781418 sameAs 2091781418 @default.
- W2091781418 citedByCount "32" @default.
- W2091781418 countsByYear W20917814182013 @default.
- W2091781418 countsByYear W20917814182015 @default.
- W2091781418 countsByYear W20917814182021 @default.
- W2091781418 crossrefType "journal-article" @default.
- W2091781418 hasAuthorship W2091781418A5015397357 @default.
- W2091781418 hasAuthorship W2091781418A5017625454 @default.
- W2091781418 hasAuthorship W2091781418A5025686273 @default.
- W2091781418 hasAuthorship W2091781418A5028973316 @default.
- W2091781418 hasAuthorship W2091781418A5028997035 @default.
- W2091781418 hasAuthorship W2091781418A5032408537 @default.
- W2091781418 hasAuthorship W2091781418A5040017671 @default.
- W2091781418 hasAuthorship W2091781418A5072654868 @default.
- W2091781418 hasConcept C104317684 @default.
- W2091781418 hasConcept C144024400 @default.
- W2091781418 hasConcept C147483822 @default.
- W2091781418 hasConcept C149923435 @default.
- W2091781418 hasConcept C150152722 @default.
- W2091781418 hasConcept C166957645 @default.
- W2091781418 hasConcept C180754005 @default.
- W2091781418 hasConcept C188280979 @default.
- W2091781418 hasConcept C197754878 @default.
- W2091781418 hasConcept C205649164 @default.
- W2091781418 hasConcept C2908647359 @default.
- W2091781418 hasConcept C37463918 @default.
- W2091781418 hasConcept C54355233 @default.
- W2091781418 hasConcept C86803240 @default.
- W2091781418 hasConceptScore W2091781418C104317684 @default.
- W2091781418 hasConceptScore W2091781418C144024400 @default.
- W2091781418 hasConceptScore W2091781418C147483822 @default.
- W2091781418 hasConceptScore W2091781418C149923435 @default.
- W2091781418 hasConceptScore W2091781418C150152722 @default.
- W2091781418 hasConceptScore W2091781418C166957645 @default.
- W2091781418 hasConceptScore W2091781418C180754005 @default.
- W2091781418 hasConceptScore W2091781418C188280979 @default.
- W2091781418 hasConceptScore W2091781418C197754878 @default.
- W2091781418 hasConceptScore W2091781418C205649164 @default.
- W2091781418 hasConceptScore W2091781418C2908647359 @default.
- W2091781418 hasConceptScore W2091781418C37463918 @default.
- W2091781418 hasConceptScore W2091781418C54355233 @default.
- W2091781418 hasConceptScore W2091781418C86803240 @default.
- W2091781418 hasIssue "2" @default.
- W2091781418 hasLocation W20917814181 @default.
- W2091781418 hasLocation W20917814182 @default.
- W2091781418 hasOpenAccess W2091781418 @default.
- W2091781418 hasPrimaryLocation W20917814181 @default.
- W2091781418 hasRelatedWork W1985536617 @default.
- W2091781418 hasRelatedWork W1995194052 @default.
- W2091781418 hasRelatedWork W2057298268 @default.
- W2091781418 hasRelatedWork W2090368772 @default.
- W2091781418 hasRelatedWork W2091514180 @default.
- W2091781418 hasRelatedWork W2115326399 @default.
- W2091781418 hasRelatedWork W2131298472 @default.
- W2091781418 hasRelatedWork W2239868639 @default.
- W2091781418 hasRelatedWork W2427947769 @default.
- W2091781418 hasRelatedWork W290528026 @default.
- W2091781418 hasVolume "41" @default.
- W2091781418 isParatext "false" @default.
- W2091781418 isRetracted "false" @default.
- W2091781418 magId "2091781418" @default.
- W2091781418 workType "article" @default.