Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091786516> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2091786516 endingPage "216" @default.
- W2091786516 startingPage "209" @default.
- W2091786516 abstract "The effects of (7-Ile) angiotensin III (AIII) and (1-Sar-8-Ile) angiotensin II (AII) on the pressor and steroidogenic effects of angiotensin were compared in conscious rats. (1-Sar-8-Ile) AII (500 ng/kg/min) equally inhibited the pressor responses of AII, AIII and (des-1-Asp) AI by 99% (P < 0.0001) while (7-Ile) AIII (500 ng/kg/min) was without effect. The steroidogenic effects of AII, AIII and (des-1-Asp) AI (300 ng/kg/min) were inhibited by (1-Sar-8-Ile) AII by 83%, 69% and 50%, respectively, whereas (7-Ile) AIII inhibited their steroidogenic effects by 35%, 62% and 25%. respectively. In contrast, ACTH or potassium stimulated aldosterone release was not altered by either antagonist. In sodium depleted rats, (7-Ile) AII reduced the elevated serum aldosterone levels by 64% without altering the blood pressure, while (1-Sar-8-Ile) AII lowered the blood pressure without altering the concentration of aldosterone present in the serum. Thus, (7-Ile) AIII is relatively selective in its ability to antagonize the adrenal actions of endogenous and exogenous angiontensins when compared to the pressor actions of these peptides. Furthermore, these angiotensin antagonists appear to be useful as pharmacologic tools in assessing the characteristics of the angiotensin receptors in a particular tissue." @default.
- W2091786516 created "2016-06-24" @default.
- W2091786516 creator A5014603417 @default.
- W2091786516 creator A5015231875 @default.
- W2091786516 date "1979-03-01" @default.
- W2091786516 modified "2023-10-03" @default.
- W2091786516 title "(7-Ile) angiotensin III: A relatively selective antagonist of angiotensin steroidogenesis" @default.
- W2091786516 cites W1967829698 @default.
- W2091786516 cites W1979260364 @default.
- W2091786516 cites W1990746566 @default.
- W2091786516 cites W1997110565 @default.
- W2091786516 cites W2012441754 @default.
- W2091786516 cites W2024296544 @default.
- W2091786516 cites W2058871240 @default.
- W2091786516 cites W2065034677 @default.
- W2091786516 cites W2087665939 @default.
- W2091786516 cites W2092539344 @default.
- W2091786516 cites W2095125029 @default.
- W2091786516 cites W2100146547 @default.
- W2091786516 cites W2145036886 @default.
- W2091786516 cites W2152978243 @default.
- W2091786516 cites W2154316132 @default.
- W2091786516 cites W2163906229 @default.
- W2091786516 cites W2171913695 @default.
- W2091786516 doi "https://doi.org/10.1016/0014-2999(79)90079-7" @default.
- W2091786516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/218823" @default.
- W2091786516 hasPublicationYear "1979" @default.
- W2091786516 type Work @default.
- W2091786516 sameAs 2091786516 @default.
- W2091786516 citedByCount "12" @default.
- W2091786516 crossrefType "journal-article" @default.
- W2091786516 hasAuthorship W2091786516A5014603417 @default.
- W2091786516 hasAuthorship W2091786516A5015231875 @default.
- W2091786516 hasBestOaLocation W20917865161 @default.
- W2091786516 hasConcept C104849204 @default.
- W2091786516 hasConcept C126322002 @default.
- W2091786516 hasConcept C134018914 @default.
- W2091786516 hasConcept C170493617 @default.
- W2091786516 hasConcept C185592680 @default.
- W2091786516 hasConcept C198710026 @default.
- W2091786516 hasConcept C2776885963 @default.
- W2091786516 hasConcept C2778525890 @default.
- W2091786516 hasConcept C2908560794 @default.
- W2091786516 hasConcept C2908929049 @default.
- W2091786516 hasConcept C71924100 @default.
- W2091786516 hasConcept C84393581 @default.
- W2091786516 hasConcept C86803240 @default.
- W2091786516 hasConceptScore W2091786516C104849204 @default.
- W2091786516 hasConceptScore W2091786516C126322002 @default.
- W2091786516 hasConceptScore W2091786516C134018914 @default.
- W2091786516 hasConceptScore W2091786516C170493617 @default.
- W2091786516 hasConceptScore W2091786516C185592680 @default.
- W2091786516 hasConceptScore W2091786516C198710026 @default.
- W2091786516 hasConceptScore W2091786516C2776885963 @default.
- W2091786516 hasConceptScore W2091786516C2778525890 @default.
- W2091786516 hasConceptScore W2091786516C2908560794 @default.
- W2091786516 hasConceptScore W2091786516C2908929049 @default.
- W2091786516 hasConceptScore W2091786516C71924100 @default.
- W2091786516 hasConceptScore W2091786516C84393581 @default.
- W2091786516 hasConceptScore W2091786516C86803240 @default.
- W2091786516 hasIssue "3" @default.
- W2091786516 hasLocation W20917865161 @default.
- W2091786516 hasLocation W20917865162 @default.
- W2091786516 hasOpenAccess W2091786516 @default.
- W2091786516 hasPrimaryLocation W20917865161 @default.
- W2091786516 hasRelatedWork W1974641745 @default.
- W2091786516 hasRelatedWork W2000504504 @default.
- W2091786516 hasRelatedWork W2001195849 @default.
- W2091786516 hasRelatedWork W2016647631 @default.
- W2091786516 hasRelatedWork W2026625444 @default.
- W2091786516 hasRelatedWork W2072353936 @default.
- W2091786516 hasRelatedWork W2077998387 @default.
- W2091786516 hasRelatedWork W2092013225 @default.
- W2091786516 hasRelatedWork W2126797993 @default.
- W2091786516 hasRelatedWork W4247631657 @default.
- W2091786516 hasVolume "54" @default.
- W2091786516 isParatext "false" @default.
- W2091786516 isRetracted "false" @default.
- W2091786516 magId "2091786516" @default.
- W2091786516 workType "article" @default.