FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091792783> ?p ?o ?g. }

• W2091792783 abstract "There is an open reading frame between ATG1022 and TGA1205 in the E3 transcription unit of adenovirus 2 that could encode a protein of MW 6700 (6.7K) (61 amino acids). To address whether this protein is expressed, we prepared an antiserum against a synthetic peptide corresponding to residues 47-61 in the 6.7K protein. This antiserum immunoprecipitated two series of protein bands, a 7K-8K doublet and a 15K-16K doublet or triplet, as observed by electrophoresis on 10-18% gradient SDS-polyacrylamide gels. These bands were not obtained from cells infected with mutants that lack the 6.7K gene. Most, if not all, of the 7K-8K and 15K-16K bands were detected by immunoblot, indicating that they are modified versions of the 6.7K protein. Only an 8K band was observed after cell-free translation of hybridization-purified mRNA, suggesting that this may be the primary translation product. As judged by DNA sequence, the 6.7K protein has a hydrophobic domain of at least 22 residues (residues 16-37), suggesting that 6.7K may be a membrane protein. Consistent with this, the 7K-8K and 15K-16K bands were observed in the crude membrane but not the cytosol or nuclear fractions of biochemically fractionated cells. The 6.7K protein was underproduced by mutants which underproduce E3 mRNAs a and c, indicating that 6.7K is translated from these mRNAs. Since the E3-gp 19K protein is also translated from mRNAs a and c, these mRNAs are bicistronic. The 6.7K protein is well-conserved in Ad5 (Ad2 and Ad5 are group C adenoviruses), and appears to be marginally conserved in Ad3 (group B)." @default.
• W2091792783 created "2016-06-24" @default.
• W2091792783 creator A5003033435 @default.
• W2091792783 creator A5032387026 @default.
• W2091792783 creator A5053052315 @default.
• W2091792783 creator A5063522218 @default.
• W2091792783 creator A5080845131 @default.
• W2091792783 creator A5081236075 @default.
• W2091792783 date "1990-09-01" @default.
• W2091792783 modified "2023-09-23" @default.
• W2091792783 title "A 6700 MW membrane protein is encoded by region E3 of adenovirus type 2" @default.
• W2091792783 cites W1486479332 @default.
• W2091792783 cites W1506671456 @default.
• W2091792783 cites W1513996696 @default.
• W2091792783 cites W1625560485 @default.
• W2091792783 cites W1779634392 @default.
• W2091792783 cites W1798647599 @default.
• W2091792783 cites W1916881887 @default.
• W2091792783 cites W1957503019 @default.
• W2091792783 cites W1968149970 @default.
• W2091792783 cites W1973106610 @default.
• W2091792783 cites W1977240898 @default.
• W2091792783 cites W1983303434 @default.
• W2091792783 cites W2009075135 @default.
• W2091792783 cites W2019428281 @default.
• W2091792783 cites W2021841238 @default.
• W2091792783 cites W2032345713 @default.
• W2091792783 cites W2033785962 @default.
• W2091792783 cites W2034436477 @default.
• W2091792783 cites W2034965106 @default.
• W2091792783 cites W2037204351 @default.
• W2091792783 cites W2049021232 @default.
• W2091792783 cites W2051123153 @default.
• W2091792783 cites W2066780628 @default.
• W2091792783 cites W2068757103 @default.
• W2091792783 cites W2070706683 @default.
• W2091792783 cites W2080110672 @default.
• W2091792783 cites W2086093618 @default.
• W2091792783 cites W2097238022 @default.
• W2091792783 cites W2102626689 @default.
• W2091792783 cites W2115668720 @default.
• W2091792783 cites W2165691362 @default.
• W2091792783 cites W2168847939 @default.
• W2091792783 cites W2174322658 @default.
• W2091792783 cites W349100877 @default.
• W2091792783 cites W4247208300 @default.
• W2091792783 doi "https://doi.org/10.1016/0042-6822(90)90395-8" @default.
• W2091792783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1697127" @default.
• W2091792783 hasPublicationYear "1990" @default.
• W2091792783 type Work @default.
• W2091792783 sameAs 2091792783 @default.
• W2091792783 citedByCount "33" @default.
• W2091792783 countsByYear W20917927832017 @default.
• W2091792783 crossrefType "journal-article" @default.
• W2091792783 hasAuthorship W2091792783A5003033435 @default.
• W2091792783 hasAuthorship W2091792783A5032387026 @default.
• W2091792783 hasAuthorship W2091792783A5053052315 @default.
• W2091792783 hasAuthorship W2091792783A5063522218 @default.
• W2091792783 hasAuthorship W2091792783A5080845131 @default.
• W2091792783 hasAuthorship W2091792783A5081236075 @default.
• W2091792783 hasConcept C104317684 @default.
• W2091792783 hasConcept C105580179 @default.
• W2091792783 hasConcept C144647389 @default.
• W2091792783 hasConcept C149364088 @default.
• W2091792783 hasConcept C153911025 @default.
• W2091792783 hasConcept C159654299 @default.
• W2091792783 hasConcept C203014093 @default.
• W2091792783 hasConcept C41625074 @default.
• W2091792783 hasConcept C55493867 @default.
• W2091792783 hasConcept C71829478 @default.
• W2091792783 hasConcept C86803240 @default.
• W2091792783 hasConcept C91523082 @default.
• W2091792783 hasConceptScore W2091792783C104317684 @default.
• W2091792783 hasConceptScore W2091792783C105580179 @default.
• W2091792783 hasConceptScore W2091792783C144647389 @default.
• W2091792783 hasConceptScore W2091792783C149364088 @default.
• W2091792783 hasConceptScore W2091792783C153911025 @default.
• W2091792783 hasConceptScore W2091792783C159654299 @default.
• W2091792783 hasConceptScore W2091792783C203014093 @default.
• W2091792783 hasConceptScore W2091792783C41625074 @default.
• W2091792783 hasConceptScore W2091792783C55493867 @default.
• W2091792783 hasConceptScore W2091792783C71829478 @default.
• W2091792783 hasConceptScore W2091792783C86803240 @default.
• W2091792783 hasConceptScore W2091792783C91523082 @default.
• W2091792783 hasLocation W20917927831 @default.
• W2091792783 hasLocation W20917927832 @default.
• W2091792783 hasOpenAccess W2091792783 @default.
• W2091792783 hasPrimaryLocation W20917927831 @default.
• W2091792783 hasRelatedWork W156140779 @default.
• W2091792783 hasRelatedWork W1583547731 @default.
• W2091792783 hasRelatedWork W1999347022 @default.
• W2091792783 hasRelatedWork W2011477816 @default.
• W2091792783 hasRelatedWork W2086567214 @default.
• W2091792783 hasRelatedWork W2092538393 @default.
• W2091792783 hasRelatedWork W209401580 @default.
• W2091792783 hasRelatedWork W2115668720 @default.
• W2091792783 hasRelatedWork W2505719210 @default.
• W2091792783 hasRelatedWork W2183876490 @default.
• W2091792783 isParatext "false" @default.
• W2091792783 isRetracted "false" @default.

• next