Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091799550> ?p ?o ?g. }
- W2091799550 endingPage "21" @default.
- W2091799550 startingPage "8" @default.
- W2091799550 abstract "An endogenous modulator for the site labeled by [ 3 H]imipramine which is putatively coupled to the serotonin transporter in human platelets was isolated and purified from plasma. Procrdures included sequential chromatography on Cibacron blue-Sepharose 4B, concanavalin A-Sepharose 4B, Mono Q HR 10/10 anion exchange, DuPont GF-250 gel permeation and Mono S HR 5/5 cation exchange columns. The purified modulator is a protein of M r 45 000 with a very acidic p K (less than 3) and sensitive to various proteinases but heat- and acid-stable. This protein inhibited [ 3 H]imipramine binding to platelet membranes competitively (IC 50 ≈6 μ M) and enhanced serotonin uptake in fresh human platelets (EC 50 ≈7 μ M). Various physico-chemical properties, including chromatographic, electrophoretic and immunological as well as amino acid composition analysis revealed that the isolated protein is most probably the human α 1 -acid glycoprotein." @default.
- W2091799550 created "2016-06-24" @default.
- W2091799550 creator A5018353777 @default.
- W2091799550 creator A5034675034 @default.
- W2091799550 creator A5064210986 @default.
- W2091799550 date "1987-01-01" @default.
- W2091799550 modified "2023-09-27" @default.
- W2091799550 title "Purification and properties of a human plasma endogenous modulator for the platelet tricyclic binding/serotonin transport complex" @default.
- W2091799550 cites W1557955277 @default.
- W2091799550 cites W1961568575 @default.
- W2091799550 cites W1966750852 @default.
- W2091799550 cites W1970155431 @default.
- W2091799550 cites W1970942750 @default.
- W2091799550 cites W1982307685 @default.
- W2091799550 cites W1991618005 @default.
- W2091799550 cites W1992879498 @default.
- W2091799550 cites W1996886584 @default.
- W2091799550 cites W2004278098 @default.
- W2091799550 cites W2010928495 @default.
- W2091799550 cites W2021986991 @default.
- W2091799550 cites W2024481516 @default.
- W2091799550 cites W2028670208 @default.
- W2091799550 cites W2041150689 @default.
- W2091799550 cites W2044670137 @default.
- W2091799550 cites W2049046640 @default.
- W2091799550 cites W2053859332 @default.
- W2091799550 cites W2057514674 @default.
- W2091799550 cites W2057679519 @default.
- W2091799550 cites W2058978917 @default.
- W2091799550 cites W2063256967 @default.
- W2091799550 cites W2076300996 @default.
- W2091799550 cites W2080084127 @default.
- W2091799550 cites W2081806580 @default.
- W2091799550 cites W2100837269 @default.
- W2091799550 cites W2128635872 @default.
- W2091799550 cites W2158907779 @default.
- W2091799550 cites W2275032446 @default.
- W2091799550 cites W1942102367 @default.
- W2091799550 doi "https://doi.org/10.1016/0304-4165(87)90119-x" @default.
- W2091799550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3542053" @default.
- W2091799550 hasPublicationYear "1987" @default.
- W2091799550 type Work @default.
- W2091799550 sameAs 2091799550 @default.
- W2091799550 citedByCount "47" @default.
- W2091799550 crossrefType "journal-article" @default.
- W2091799550 hasAuthorship W2091799550A5018353777 @default.
- W2091799550 hasAuthorship W2091799550A5034675034 @default.
- W2091799550 hasAuthorship W2091799550A5064210986 @default.
- W2091799550 hasConcept C108625454 @default.
- W2091799550 hasConcept C142724271 @default.
- W2091799550 hasConcept C16613235 @default.
- W2091799550 hasConcept C170493617 @default.
- W2091799550 hasConcept C179247698 @default.
- W2091799550 hasConcept C181199279 @default.
- W2091799550 hasConcept C185592680 @default.
- W2091799550 hasConcept C19869320 @default.
- W2091799550 hasConcept C202751555 @default.
- W2091799550 hasConcept C203014093 @default.
- W2091799550 hasConcept C204787440 @default.
- W2091799550 hasConcept C206967267 @default.
- W2091799550 hasConcept C2775864247 @default.
- W2091799550 hasConcept C2779145073 @default.
- W2091799550 hasConcept C41625074 @default.
- W2091799550 hasConcept C43617362 @default.
- W2091799550 hasConcept C55493867 @default.
- W2091799550 hasConcept C71924100 @default.
- W2091799550 hasConcept C86803240 @default.
- W2091799550 hasConcept C89560881 @default.
- W2091799550 hasConceptScore W2091799550C108625454 @default.
- W2091799550 hasConceptScore W2091799550C142724271 @default.
- W2091799550 hasConceptScore W2091799550C16613235 @default.
- W2091799550 hasConceptScore W2091799550C170493617 @default.
- W2091799550 hasConceptScore W2091799550C179247698 @default.
- W2091799550 hasConceptScore W2091799550C181199279 @default.
- W2091799550 hasConceptScore W2091799550C185592680 @default.
- W2091799550 hasConceptScore W2091799550C19869320 @default.
- W2091799550 hasConceptScore W2091799550C202751555 @default.
- W2091799550 hasConceptScore W2091799550C203014093 @default.
- W2091799550 hasConceptScore W2091799550C204787440 @default.
- W2091799550 hasConceptScore W2091799550C206967267 @default.
- W2091799550 hasConceptScore W2091799550C2775864247 @default.
- W2091799550 hasConceptScore W2091799550C2779145073 @default.
- W2091799550 hasConceptScore W2091799550C41625074 @default.
- W2091799550 hasConceptScore W2091799550C43617362 @default.
- W2091799550 hasConceptScore W2091799550C55493867 @default.
- W2091799550 hasConceptScore W2091799550C71924100 @default.
- W2091799550 hasConceptScore W2091799550C86803240 @default.
- W2091799550 hasConceptScore W2091799550C89560881 @default.
- W2091799550 hasIssue "1" @default.
- W2091799550 hasLocation W20917995501 @default.
- W2091799550 hasLocation W20917995502 @default.
- W2091799550 hasOpenAccess W2091799550 @default.
- W2091799550 hasPrimaryLocation W20917995501 @default.
- W2091799550 hasRelatedWork W1965252847 @default.
- W2091799550 hasRelatedWork W1985822756 @default.
- W2091799550 hasRelatedWork W1997085757 @default.
- W2091799550 hasRelatedWork W2024459028 @default.
- W2091799550 hasRelatedWork W2027701078 @default.